1.1.1.238: 12beta-hydroxysteroid dehydrogenase

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For detailed information about 12beta-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

Synonyms

12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.238 12beta-hydroxysteroid dehydrogenase

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Results

in table

1

Application

1

CAS Registry Number

2

Cofactor

1

General Stability

9

KM Value [mM]

1

Localization

1

Molecular Weight [Da]

1

Organism

2

Pathway

2

pH Optimum

1

pH Range

1

pH Stability

1

Reaction

3

Reaction Type

1

Reference

2

Specific Activity [micromol/min/mg]

1

Storage Stability

8

Substrates and Products (Substrate)

1

Synonyms

1

Systematic Name

3

Temperature Stability [°C]

Reaction

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Reaction on EC 1.1.1.238 - 12beta-hydroxysteroid dehydrogenase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

3alpha,7alpha,12beta-trihydroxy-5beta-cholan-24-oate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate + NADPH + H+

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