1.1.1.255: mannitol dehydrogenase

This is an abbreviated version!
For detailed information about mannitol dehydrogenase, go to the full flat file.

Reaction

Synonyms

mannitol 1-dehydrogenase, mannitol 1-oxidoreductase, mannitol:mannose 1-oxidoreductase, MTD, NAD-dependent mannitol dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.255 mannitol dehydrogenase

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1	Activating Compound
109	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
7	Cofactor
1	General Information
12	Inhibitors
8	KM Value [mM]
3	Localization
4	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
15	Organism
1	Pathway
3	pH Range
2	Purification (Commentary)
1	Reaction
3	Reaction Type
13	Reference
20	Source Tissue
5	Specific Activity [micromol/min/mg]
2	Storage Stability
21	Substrates and Products (Substrate)
1	Subunits
9	Synonyms
1	Systematic Name

Reaction

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Reaction on EC 1.1.1.255 - mannitol dehydrogenase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

D-mannitol + NAD+ = D-mannose + NADH + H+

The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation. The enzyme is specific for NAD+ and does not use NADP+

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