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1.1.1.265: 3-methylbutanal reductase

This is an abbreviated version!
For detailed information about 3-methylbutanal reductase, go to the full flat file.

Word Map on EC 1.1.1.265

Reaction

3-Methylbutanol
+
NAD(P)+
=
3-Methylbutanal
+
NAD(P)H
+
H+

Synonyms

More, aldehyde reductase, 3-methylbutyraldehyde reductase, isoamylaldehyde reductase, isopentanal reductase, isovaleral reductase, isovaleraldehyde reductase, branched-chain alcohol dehydrogenase, bcADH, GRE2 gene product, Gre2p, YOL151w gene product, Gre2, YOL151W, YMR152W, Ymr152wp, YIM1, protein YIM1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.265 3-methylbutanal reductase

Inhibitors

Inhibitors on EC 1.1.1.265 - 3-methylbutanal reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
2-methylbutanal
-
presence of NADPH, Ki: 2.74 mM, presence of NADH, Ki: 4.61 mM
3-Methylbutanal
-
presence of NADPH, Ki: 7.14 mM, presence of NADH, Ki: 253 mM
Butanal
-
presence of NADPH, Ki: 16.6 mM
dithiothreitol
-
35% inhibition at 5 mM
glutathione
-
24% inhibition at 5 mM
Heptanal
-
presence of NADPH, Ki: 0.88 mM, presence of NADH, Ki: 1.17 mM
hexanal
-
presence of NADPH, Ki: 0.79 mM, presence of NADH, Ki: 2.8 mM
NADP+
-
complete inhibition at a 6.7fold excess of NADP+ in a reduction assay with 0.15 mM NADH
pentanal
-
presence of NADPH, Ki: 3.9 mM, presence of NADH, Ki: 13.9 mM
propanal
-
presence of NADPH, Ki: 46.6 mM
quercetin
-
78% inhibition at 0.1 mM
sodium valporate
-
5% inhibition at 1 mM
additional information
-