1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase

This is an abbreviated version!
For detailed information about 1-deoxy-D-xylulose-5-phosphate reductoisomerase, go to the full flat file.

Reaction

Synonyms

1-deoxy-D-xylulose 5-phosphate isomeroreductase, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 1-deoxy-D-xylulose-5-phosphate, 1-deoxy-D-xylulose-5-phosphate reductoisomerase, 1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose 5-phosphate reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase, 2C-methyl-D-erythritol 4-phosphate synthase, 2C-methyl-D-erythritol-4-phosphate synthase, AaDXR, CaDXR, deoxyxylulose 5-phosphate reductoisomerase, deoxyxylulosephosphate reductoisomerase, DOXP reductoisomerase, DOXP-reductoisomerase, DXP reductoisomerase, DXP-reductoisomerase, DXR, DXR1, DzDXR, EcDXR, FtIspC, IspC, MEP synthase, meps, methylerythritol phosphate synthase, MtbIspC, MtDXR, Os01g01710, OsDXR, PdDXR, PfDXR, PtDXR, Rv2870c, SaDXR, VvDxr, YpIspC

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase

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Results	in table
7	Activating Compound
35608	AA Sequence
29	Application
1	CAS Registry Number
58	Cloned(Commentary)
106	Cofactor
16	Crystallization (Commentary)
10	Expression
64	General Information
162	IC50 Value
385	Inhibitors
14	kcat/KM [mM/s]
64	Ki Value [mM]
85	KM Value [mM]
21	Localization
76	Metals/Ions
24	Molecular Weight [Da]
66	Natural Substrates/ Products (Substrates)
540	Organism
7	Pathway
136	PDB ID
30	pH Optimum
1	pH Range
1	pH Stability
6	pI Value
4	Posttranslational Modification
47	Protein Variants
28	Purification (Commentary)
14	Reaction
3	Reaction Type
134	Reference
92	Source Tissue
8	Specific Activity [micromol/min/mg]
8	Storage Stability
141	Substrates and Products (Substrate)
29	Subunits
190	Synonyms
1	Systematic Name
29	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Temperature Stability [°C]
36	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.1.1.267 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C

Escherichia coli

-

697249

-20°C, 50% glycerol, fully active for over 12 months

Mycobacterium tuberculosis

-

654748

-20°C, purifed recombinant enzyme, 0.1 M Tris-HCl, pH 7.5, with 50 mM KCl, 10% v/v glycerol, and 10 mM DTT, 6 months, 56% remaining activity

Arabidopsis thaliana

Q9XFS9

673562

-70°C

Plasmodium falciparum

-

697249

-80°C, purifed recombinant enzyme, 0.1 M Tris-HCl, pH 7.5, with 50 mM KCl, 10% v/v glycerol, and 10 mM DTT, 6 months, no loss of activity

Arabidopsis thaliana

Q9XFS9

673562

4°C, 100 mM Tris-HCl pH 7.5, 1 month

Escherichia coli

P45568

286428

4°C, half-life about 3 days

Mycobacterium tuberculosis

-

654748

4°C, purifed recombinant enzyme, 0.1 M Tris-HCl, pH 7.5, with 50 mM KCl, 10% v/v glycerol, and 10 mM DTT, 6 months, 4% remaining activity

Arabidopsis thaliana

Q9XFS9

673562