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1.1.1.269: 2-(S)-hydroxypropyl-CoM dehydrogenase

This is an abbreviated version!
For detailed information about 2-(S)-hydroxypropyl-CoM dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.269

Reaction

(2S)-2-hydroxypropyl-CoM
+
NAD+
=
2-oxopropyl-CoM
 +
NADH
 +
H+

Synonyms

(S)-hydroxypropyl-coenzyme M dehydrogenase, (S)-hydroxypropylthioethanesulfonate dehydrogenase, 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase, HPCDH3, S-HPCDH, xecE, xecE1, xecE3

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase

Reference

topprint

Reference on EC 1.1.1.269 - 2-(S)-hydroxypropyl-CoM dehydrogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Krum, J.G.; Ensign, S.A.
Evidence that a linear megaplasmid encodes enzymes of aliphatic alkene and epoxide metabolism and coenzyme M (2-mercaptoethanesulfonate) biosynthesis in Xanthobacter strain Py2
J. Bacteriol.
183
2172-2177
2001
Xanthobacter sp., Xanthobacter sp. Py2
Manually annotated by BRENDA team
Krishnakumar, A.M.; Nocek, B.P.; Clark, D.D.; Ensign, S.A.; Peters, J.W.
Structural basis for stereoselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases
Biochemistry
45
8831-8840
2006
Xanthobacter autotrophicus
Manually annotated by BRENDA team
Sliwa, D.A.; Krishnakumar, A.M.; Peters, J.W.; Ensign, S.A.
Molecular basis for enantioselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases, a unique pair of stereoselective short-chain dehydrogenases/reductases involved in aliphatic epoxide carboxylation
Biochemistry
49
3487-3498
2010
Xanthobacter autotrophicus, Xanthobacter autotrophicus (Q56841)
Manually annotated by BRENDA team
Bakelar, J.W.; Sliwa, D.A.; Johnson, S.J.
Crystal structures of S-HPCDH reveal determinants of stereospecificity for R- and S-hydroxypropyl-coenzyme M dehydrogenases
Arch. Biochem. Biophys.
533
62-68
2013
Xanthobacter autotrophicus (A7IQH5), Xanthobacter autotrophicus
Manually annotated by BRENDA team
Clark, D.D.
Characterization of the recombinant (R)- and (S)-hydroxypropyl-coenzyme M dehydrogenases A case study to augment the teaching of enzyme kinetics and stereoselectivity
Biochem. Mol. Biol. Educ.
47
124-132
2019
Xanthobacter autotrophicus (Q56841), Xanthobacter autotrophicus ATCC BAA-1158 (Q56841)
Manually annotated by BRENDA team