1.1.1.282: quinate/shikimate dehydrogenase

This is an abbreviated version!
For detailed information about quinate/shikimate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.282

Reaction

L-quinate
+
NAD(P)+
=
3-dehydroquinate
+
NAD(P)H
+
H+

Synonyms

cgl0424, cgR_0495, dehydroquinate dehydratase-shikimate dehydrogenase, More, Poptr2, Poptr3, Poptr4, QSDH, qsuD, quinate/shikimate 5-dehydrogenase, quinate/shikimate dehydrogenase, rifI, RifI2, SDH, SDH/QDH, sdhL, shikimate/quinate dehydrogenase, YdiB

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.282 quinate/shikimate dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.282 - quinate/shikimate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-dehydroquinate + NADPH + H+
L-quinate + NADP+
show the reaction diagram
3-dehydroshikimate + NAD(P)H + H+
shikimate + NAD(P)+
show the reaction diagram
YdiB catalyzes the reduction of 3-dehydroshikimate to shikimate as part of the shikimate pathway
-
-
?
3-dehydroshikimate + NADH + H+
shikimate + NAD+
show the reaction diagram
-
-
-
r
dihydroshikimate + NAD+
(1S,3R,4S)-3,4-dihydroxy-5-oxocyclohexanecarboxylic acid + NADH + H+
show the reaction diagram
L-quinate + 3-acetylpyridine adenine dinucleotide
3-dehydroquinate + ?
show the reaction diagram
L-quinate + beta-NAD+
3-dehydroquinate + beta-NADH + H+
show the reaction diagram
L-quinate + NAD(P)+
3-dehydroquinate + NAD(P)H + H+
show the reaction diagram
L-quinate + NAD+
3-dehydroquinate + NADH + H+
show the reaction diagram
L-quinate + NAD+
4-dehydroquinate + NADH + H+
show the reaction diagram
L-quinate + NADP+
3-dehydroquinate + NADPH + H+
show the reaction diagram
L-quinate + nicotinamide 1,N6-ethenoadenine dinucleotide
3-dehydroquinate + ?
show the reaction diagram
-
69% of the activity with NAD+
-
-
?
L-quinate + nicotinamide hypoxanthine dinucleotide
3-dehydroquinate + ?
show the reaction diagram
-
1.3fold higher activity than with NAD+
-
-
?
L-quinate + oxidized nicotinamide 1,N6-ethanoadenine dinucleotide
3-dehydroquinate + reduced nicotinamide 1,N6-ethanoadenine dinucleotide
show the reaction diagram
-
69% activity compared to NAD+
-
-
r
quinate + NAD(P)+
3-dehydroquinate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
shikimate + NAD(P)+
3-dehydroshikimate + NAD(P)H + H+
show the reaction diagram
shikimate + NAD+
3-dehydroshikimate + NADH + H+
show the reaction diagram
shikimate + NADP+
3-dehydroshikimate + NADPH + H+
show the reaction diagram
t-3,t-4-dihydroxycyclohexane-c-1-carboxylate + NAD+
4-hydroxy-3-oxocyclohexane-c-1-carboxylate + NADH + H+
show the reaction diagram
-
highly stereospecific with regard to hydroaromatic substrates, oxidizes only the axial hydroxyl group at C-3 of the (-)-enantiomer, 44% of the activity with (-)-quinate
(-)-isomer, reverse reaction: 2.2fold higher activity than with (-)-3-dehydroquinate
-
r
t-3-hydroxy-4-oxocyclohexane-c-1-carboxylate + NAD+
?
show the reaction diagram
-
6% of the activity with (-)-quinate
-
-
?
additional information
?
-