1.1.1.291: 2-hydroxymethylglutarate dehydrogenase

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For detailed information about 2-hydroxymethylglutarate dehydrogenase, go to the full flat file.

Reaction

Synonyms

HgD

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.291 2-hydroxymethylglutarate dehydrogenase

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Results	in table
687	AA Sequence
1	Cloned(Commentary)
2	Cofactor
2	KM Value [mM]
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	Oxidation Stability
3	Pathway
4	PDB ID
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.1.1.291 - 2-hydroxymethylglutarate dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-formylglutarate + NADH + H+

2-hydroxymethylglutarate + NAD+

Eubacterium barkeri

-

the enzyme forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri

670692

-

-

?

2-hydroxymethylglutarate + NAD+

2-formylglutarate + NADH + H+

Eubacterium barkeri

-

-

670692

-

-

r