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1.1.1.3: homoserine dehydrogenase

This is an abbreviated version!
For detailed information about homoserine dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.3

Reaction

L-homoserine
+
NAD(P)+
=
L-aspartate 4-semialdehyde
+
NAD(P)H
+
H+

Synonyms

AK-HDH, AK-HSD-1, AK-HSDH, AK-HseDH, aspartate kinase-homoserine dehydrogenase, aspartokinase-homoserine dehydrogenase I, bifunctional aspartate kinase-homoserine dehydrogenase, BsHSD, HDH, hom, hom-1, Hom6, homoserine dehydrogenase 1, homoserine dehydrogenase 2, HSD, HSDH, HseDH, More, orf19.2951, PbHSD, SACOL1362, StHSD, thrA, TM_0547, TTHA0489, TtHSD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.3 homoserine dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.3 - homoserine dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
110000
-
gel filtration, sedimentation equilibrium centrifugation
168000 - 174000
190000
-
gel filtration threonine sensitive isozyme
220000
221000
recombinant His-tagged enzyme, gel filtration
280000
-
disc gel electrophoresis, threonine sensitive isozyme
290000
-
gel filtration, threonine sensitive isozyme
320000
34000
-
gel filtration, isozyme II, cytoplasm
38000
-
2 * 38000, SDS-PAGE, threonine resistant isozyme
40000
40600
2 * 40600, calculated, 2 * 40000, SDS-PAGE
450000
about, recombinant enzyme, gel filtration
470000
55000
69000
-
gel filtration, isozyme II, cytoplasm
70000
75000
80000
-
disc gel electrophoresis, threonine insensitive isozyme
81000
-
gel filtration
85000
-
x * 85000, SDS-PAGE, threonine sensitive isozyme
89000
-
x * 89000 + x * 93000, SDS-PAGE, threonine sensitive isozyme
92000
gel filtration, recombinant His-tagged enzyme HseDH
93000
-
x * 89000 + x * 93000, SDS-PAGE, threonine sensitive isozyme