1.1.1.306: S-(hydroxymethyl)mycothiol dehydrogenase

This is an abbreviated version, for detailed information about S-(hydroxymethyl)mycothiol dehydrogenase, go to the full flat file.

Reaction

S-(hydroxymethyl)mycothiol
+
NAD+
=
S-formylmycothiol
+
NADH
+
H+

Synonyms

FD-FA1DH, glutathione-independent formaldehyde dehydrogenase, MD-FALDH, mFADH, MSH-dependent formaldehyde dehydrogenase, mycothiol-dependent formaldehyde dehydroganse, NAD/factor-dependent formaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.306 S-(hydroxymethyl)mycothiol dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.306 - S-(hydroxymethyl)mycothiol dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8 - 9.5
-
optimal in Na-diphosphate buffer, buffers containing amino groups give poor activity, possibly because of Schiff base formation with formaldehyde
9
-
formaldehyde as substrate
10.2
-
alcohols as substrates