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1.1.1.311: (S)-1-phenylethanol dehydrogenase

This is an abbreviated version!
For detailed information about (S)-1-phenylethanol dehydrogenase, go to the full flat file.

Wordmap for 1.1.1.311

Word Map on EC 1.1.1.311 Wordmap for 1.1.1.311

Reaction

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(S)-1-phenylethanol
+
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NAD+
=
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acetophenone
 +
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NADH
 +
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H+

Synonyms

(S)-PED, PED, PedH, prelog-specific NADH-dependent (S)-1-phenylethanol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.3111.1.1.311 (S)-1-phenylethanol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.311 - (S)-1-phenylethanol dehydrogenase

for references in articles please use BRENDA:EC1.1.1.311

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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-1-phenylethanol + NAD+
acetophenone + NADH + H+
show the reaction diagram
2,2,2-trifluoroacetophenone + NADH + H+
(S)-1-phenyl-2,2,2-trifluoroethan-1-ol + NAD+
show the reaction diagram
2,2-dichloroacetophenone + NADH + H+
? + NAD+
show the reaction diagram
Substrates: -
Products: -
r
2,4'-dichloroacetophenone + NADH + H+
(S)-2-chloro-1-(4-chloro-phenyl)-ethanol + NAD+
show the reaction diagram
2-acetylpyridine + NADH + H+
? + NAD+
show the reaction diagram
2-chloroacetophenone + NADH + H+
? + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-bromoacetophenone + NADH + H+
(S)-4-(1-bromoethyl)phenol + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-chloroacetophenone + NADH + H+
(S)-4-(1-chloroethyl)phenol + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-ethylacetophenone + NADH + H+
? + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-fluoroacetophenone + NADH + H+
(S)-4-(1-fluoroethyl)phenol + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-hydroxyacetophenone + NADH + H+
(S)-4-(1-hydroxyethyl)phenol + NAD+
show the reaction diagram
4'-methoxyacetophenone + NADH + H+
(S)-4-(1-methoxyethyl)phenol + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4'-nitroacetophenone + NADH + H+
(S)-4-(1-nitroethyl)phenol + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4-acetylbiphenyl + NADH + H+
(S)-1-(biphenyl-4-yl)ethanol + NAD+
show the reaction diagram
4-acetylpyridine + NADH + H+
? + NAD+
show the reaction diagram
Substrates: -
Products: -
r
4-aminoacetophenone + NADH + H+
1-(4-aminophenyl)ethanol + NAD+
show the reaction diagram
acetophenone + NADH + H+
(S)-1-phenylethanol + NAD+
show the reaction diagram
methyl 4-(4-bromophenyl)-4-oxobutanoate + NADH + H+
(S)-methyl 4-(4-bromophenyl)-4-hydroxybutanoate + (S)-(-)-5-(4-bromophenyl)dihydrofuran-2(3H)-one + NAD+
show the reaction diagram
methyl 4-(4-chlorophenyl)-4-oxobutanoate + NADH + H+
(S)-methyl 4-(4-chlorophenyl)-4-hydroxybutanoate + (S)-(-)-5-(4-chlorophenyl)dihydrofuran-2(3H)-one + NAD+
show the reaction diagram
methyl 4-(4-fluorophenyl)-4-oxobutanoate + NADH + H+
(S)-methyl 4-(4-fluorophenyl)-4-hydroxybutanoate + (S)-(-)-5-(4-fluorophenyl)dihydrofuran-2(3H)-one + NAD+
show the reaction diagram
Substrates: -
Products: -
r
methyl 4-(4-methoxyphenyl)-4-oxobutanoate + NADH + H+
(S)-methyl 4-(4-methoxyphenyl)-4-hydroxybutanoate + (S)-(-)-5-(4-methoxyphenyl)dihydrofuran-2(3H)-one + NAD+
show the reaction diagram
Substrates: -
Products: -
r
methyl 4-(4-methylphenyl)-4-oxobutanoate + NADH + H+
(S)-methyl 4-(4-methylphenyl)-4-hydroxybutanoate + (S)-(-)-5-(4-methylphenyl)dihydrofuran-2(3H)-one + NAD+
show the reaction diagram
Substrates: -
Products: -
r
methyl 4-fluorobenzoylacetate + NADH + H+
(S)-methyl 3-(4-fluorophenyl)-3-hydroxypropanoate + NAD+
show the reaction diagram
Substrates: -
Products: 100% enantiomertic excess
?
methyl 4-oxo-4-(pyren-1-yl)butanoate + NADH + H+
(S)-methyl 4-hydroxy-4-(pyren-1-yl)butanoate + (S)-(-)-5-(pyren-1-yl)oxolan-2-one + NAD+
show the reaction diagram
Substrates: -
Products: -
r
methyl 4-oxo-4-phenylbutanoate + NADH + H+
(S)-methyl 4-hydroxy-4-phenylbutanoate + (S)-(-)-5-phenyldihydrofuran-2(3H)-one + NAD+
show the reaction diagram
Substrates: -
Products: -
r
additional information
?
-