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1.1.1.338: (2R)-3-sulfolactate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about (2R)-3-sulfolactate dehydrogenase (NADP+), go to the full flat file.

Reaction

(2R)-3-sulfolactate
+
NADP+
=
3-sulfopyruvate
 +
NADPH
 +
H+

Synonyms

(R)-sulfolactate dehydrogenase, (R)-sulfolactate:NAD+ oxidoreductase, (R)-sulfolactate:NADP+ oxidoreductase, ComC, L-sulfolactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)

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Results
in table
293
AA Sequence
2
Cofactor
1
Expression
4
KM Value [mM]
1
Molecular Weight [Da]
1
Organism
4
Pathway
1
Reaction
1
Reference
2
Storage Stability
3
Substrates and Products (Substrate)
1
Subunits
6
Synonyms
1
Systematic Name

Substrates Products

Substrates Products on EC 1.1.1.338 - (2R)-3-sulfolactate dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-3-sulfolactate + NADP+
3-sulfopyruvate + NADPH + H+
show the reaction diagram
specific activity for oxidation of sulfolactate is about 5% of the activity for reduction of 3-sulfopyruvate
-
-
r
3-sulfopyruvate + NADPH + H+
(S)-3-sulfolactate + NADP+
show the reaction diagram
specific activity for oxidation of sulfolactate is about 5% of the activity for reduction of 3-sulfopyruvate
-
-
r
additional information
?
-
no substrate: pyruvate, oxaloacetate, (S)-malate, (S)-lactate, (R)-malate, (R)-lactate
-
-
?