1.1.1.362: aklaviketone reductase
This is an abbreviated version!
For detailed information about aklaviketone reductase, go to the full flat file.
Reaction
Synonyms
DauE
ECTree
1.1.1.362 aklaviketone reductaseAdvanced search results
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results (| Results | in table |
|---|---|
| 38 | AA Sequence |
| 1 | Cloned(Commentary) |
| 1 | Cofactor |
| 1 | General Information |
| 1 | Molecular Weight [Da] |
| 1 | Natural Substrates/ Products (Substrates) |
| 1 | Organism |
| 7 | Pathway |
| 1 | Reaction |
| 1 | Reference |
| 4 | Substrates and Products (Substrate) |
| 1 | Subunits |
| 1 | Synonyms |
| 1 | Systematic Name |
Substrates Products
Substrates Products on EC 1.1.1.362 - aklaviketone reductase
for references in articles please use BRENDA:EC1.1.1.362
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY 
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
7-oxodaunomycinone + NADPH + H+
daunomycinone + NADP+
Substrates: -
Products: -
Products: -
?
maggiemycin + NADPH + H+
epsilon-rhodomycinone + NADP+
Substrates: -
Products: -
Products: -
?
aklaviketone + NADPH + H+
aklavinone + NADP+
Substrates: the enzyme is involved in the biosynthesis of the anthracyclins aclacinomycin and daunomycin. Aklavinone is the last intermediate common to both aclacinomycin and daunomycin biosynthesis
Products: -
Products: -
?
aklaviketone + NADPH + H+
aklavinone + NADP+
Substrates: activity with NADH is 7% of the activity with NADPH
Products: -
Products: -
?
