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1.1.1.369: D-chiro-inositol 1-dehydrogenase

This is an abbreviated version!
For detailed information about D-chiro-inositol 1-dehydrogenase, go to the full flat file.

Reaction

1D-chiro-inositol
+
NAD+
=
2D-2,3,5/4,6-pentahydroxycyclohexanone
+
NADH
+
H+

Synonyms

IDH, iolG, TM0414

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.369 D-chiro-inositol 1-dehydrogenase

Systematic Name

Systematic Name on EC 1.1.1.369 - D-chiro-inositol 1-dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
1D-chiro-inositol:NAD+ 1-oxidoreductase
The enzyme, found in the bacterium Bacillus subtilis, also catalyses the reaction of EC 1.1.1.18, inositol 2-dehydrogenase, and can also use D-glucose and D-xylose. It shows trace activity with D-ribose and D-fructose [1]. It is part of a myo-inositol/D-chiro-inositol degradation pathway leading to acetyl-CoA.