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1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about L-2-hydroxycarboxylate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.375

Reaction

a (2S)-2-hydroxycarboxylate
+
NAD(P)+
=
a 2-oxocarboxylate
 +
NAD(P)H
 +
H+

Synonyms

lactate/malate dehydrogenase, LDH-like L-MalDH, MdhII, MJ0409, MJ0490

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

Temperature Stability

Temperature Stability on EC 1.1.1.375 - L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
80
thermal transition between active and inactive enzyme starts at about 80°C and follows first-order kinetics