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1.1.1.382: ketol-acid reductoisomerase (NAD+)

This is an abbreviated version!
For detailed information about ketol-acid reductoisomerase (NAD+), go to the full flat file.

Reaction

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(2R)-2,3-dihydroxy-3-methylbutanoate
+
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NAD+
=
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(2S)-2-hydroxy-2-methyl-3-oxobutanoate
+
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NADH
+
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H+

Synonyms

ilvC

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.3821.1.1.382 ketol-acid reductoisomerase (NAD+)

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Resultsin table
43AA Sequence
4Cloned(Commentary)
4Cofactor
4Crystallization (Commentary)
4kcat/KM [mM/s]
4KM Value [mM]
9Organism
4pH Optimum
4Purification (Commentary)
1Reaction
9Reference
4Substrates and Products (Substrate)
4Synonyms
1Systematic Name
4Turnover Number [1/s]
All data fields related to EC 1.1.1.382

Sequence

Sequence on EC 1.1.1.382 - ketol-acid reductoisomerase (NAD+)

for references in articles please use BRENDA:EC1.1.1.382

Please use the AA Sequence and Transmembrane Helices Search for a specific query.

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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ILVC_DESOH
Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3)
352
0
38685
Swiss-Prot
-
ILVC_UNCAG
332
0
36857
Swiss-Prot
-
ILVC_THEPS
Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB)
332
0
36963
Swiss-Prot
-
A0A644U6P1_9ZZZZ
330
0
36337
TrEMBL
other Location (Reliability: 1)
A0A645E1R6_9ZZZZ
297
0
32294
TrEMBL
other Location (Reliability: 2)
A0A644W4P6_9ZZZZ
296
0
31989
TrEMBL
other Location (Reliability: 2)
A0A645BEA1_9ZZZZ
135
0
15605
TrEMBL
other Location (Reliability: 2)
A0A644V7T4_9ZZZZ
346
0
37488
TrEMBL
Mitochondrion (Reliability: 4)
A0A645FN88_9ZZZZ
205
0
22781
TrEMBL
other Location (Reliability: 2)
A0A644STA9_9ZZZZ
332
0
36373
TrEMBL
other Location (Reliability: 1)
A0A645DD86_9ZZZZ
252
0
28050
TrEMBL
other Location (Reliability: 1)
A0A7U9XIV6_9FIRM
259
0
28408
TrEMBL
-
A0A645H5J9_9ZZZZ
85
0
9845
TrEMBL
other Location (Reliability: 3)
A0A645JCS6_9ZZZZ
159
0
17831
TrEMBL
other Location (Reliability: 1)
A0A645EM77_9ZZZZ
56
0
6559
TrEMBL
other Location (Reliability: 2)
A0A645DWU2_9ZZZZ
205
0
22600
TrEMBL
other Location (Reliability: 3)
A0A644Z7K5_9ZZZZ
330
0
36425
TrEMBL
other Location (Reliability: 1)
A0A644WJ44_9ZZZZ
334
0
36807
TrEMBL
other Location (Reliability: 1)
A0A5E4LEX6_9ARCH
239
0
26069
TrEMBL
-
A0A645FD61_9ZZZZ
98
0
11423
TrEMBL
other Location (Reliability: 3)
A0A645IUE3_9ZZZZ
104
0
11809
TrEMBL
other Location (Reliability: 4)
A0A645AQB1_9ZZZZ
331
0
35943
TrEMBL
other Location (Reliability: 1)
A0A645JIQ6_9ZZZZ
132
0
15073
TrEMBL
other Location (Reliability: 2)
A0A644TWF5_9ZZZZ
348
0
38466
TrEMBL
other Location (Reliability: 1)
A0A644TW23_9ZZZZ
330
0
36328
TrEMBL
other Location (Reliability: 1)
A0A645H5R6_9ZZZZ
239
0
26504
TrEMBL
other Location (Reliability: 4)
A0A644VM12_9ZZZZ
333
0
36575
TrEMBL
other Location (Reliability: 1)
A0A645GJT2_9ZZZZ
209
0
23458
TrEMBL
other Location (Reliability: 4)
A0A645C9T5_9ZZZZ
84
0
9952
TrEMBL
other Location (Reliability: 1)
A0A644WKB9_9ZZZZ
317
0
34336
TrEMBL
Mitochondrion (Reliability: 5)
A0A644UBC2_9ZZZZ
333
0
36541
TrEMBL
other Location (Reliability: 2)
A0A645EG34_9ZZZZ
190
0
21455
TrEMBL
other Location (Reliability: 3)
A0A6I5ZTW5_9THEO
330
0
37027
TrEMBL
-
A0A645HQ70_9ZZZZ
210
0
23486
TrEMBL
other Location (Reliability: 2)
A0A644ZQF6_9ZZZZ
336
0
36993
TrEMBL
other Location (Reliability: 1)
A0A644V8D7_9ZZZZ
348
0
38748
TrEMBL
other Location (Reliability: 2)
ILVC_ALIAD
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / BCRC 14685 / JCM 5260 / KCTC 1825 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-IA)
344
0
37909
Swiss-Prot
-
ILVC_IGNAA
Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1)
335
0
37346
Swiss-Prot
-
ILVC_ARCFU
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
332
0
37212
Swiss-Prot
-