EC 1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
This is an abbreviated version!
For detailed information about dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase, go to the full flat file.
Reaction
Synonyms
DTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase, dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose 3-oxidoreductase, dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase, jadP, KijD10, NDP-hexose 3-ketoreductase, OleW, SpnN
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Engineering
Engineering on EC 1.1.1.384 - dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
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K102E
mutant enzyme retains some activity, but its catalytic efficiency is reduced by more than 4 orders of magnitude from that for the wild-type enzyme