1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

This is an abbreviated version!
For detailed information about dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase, go to the full flat file.

Reaction

Synonyms

DTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase, dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose 3-oxidoreductase, dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase, jadP, KijD10, NDP-hexose 3-ketoreductase, OleW, SpnN

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

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Results

in table

13

AA Sequence

2

Cloned(Commentary)

2

Cofactor

1

Crystallization (Commentary)

4

Engineering

1

Expression

2

General Information

1

KCat/KM [mM/s]

1

KM Value [mM]

3

Molecular Weight [Da]

2

Natural Substrates/ Products (Substrates)

4

Organism

9

Pathway

1

pH Optimum

1

Purification (Commentary)

1

Reaction

4

Reference

7

Substrates and Products (Substrate)

2

Subunits

8

Synonyms

1

Systematic Name

1

Temperature Optimum [°C]

1

Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.384 - dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+

dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+

Actinomadura kijaniata

B3TMR8

the enzyme is involved in the biosynthesis of dTDP-L-digitoxose

729208

-

-

?

TDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+

TDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+

Saccharopolyspora spinosa

Q9ALN5

-

731977

-

-

?