1.1.1.386: ipsdienol dehydrogenase

This is an abbreviated version!
For detailed information about ipsdienol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.386

Reaction

(R)-ipsdienol
+
NAD(P)+
=
ipsdienone
+
NAD(P)H
+
H+

Synonyms

IDOLDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.386 ipsdienol dehydrogenase

General Information

General Information on EC 1.1.1.386 - ipsdienol dehydrogenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
-
the enzyme belongs to the short-chain oxidoreductase ipsdienol dehydrogenases
metabolism
-
the enzyme is involved in pheromon production
physiological function
-
Ips spp. bark beetles use ipsdienol, ipsenol, ipsdienone and ipsenone as aggregation pheromone components and pheromone precursors. For Ips pini, the short-chain oxidoreductase ipsdienol dehydrogenase (IDOLDH) converts (R)-ipsdienol to ipsdienone, and thus likely plays a role in determining pheromone composition. Different IDOLDH orthologues and or activity levels contribute to differences in Ips spp. pheromone composition
additional information
-
the enzyme contains the typical Rossmann-fold motif for nucleotide binding and the catalytic tetrad that are highly conserved