1.1.1.386: ipsdienol dehydrogenase

This is an abbreviated version, for detailed information about ipsdienol dehydrogenase, go to the full flat file.

Reaction

(R)-ipsdienol
+
NAD(P)+
=
ipsdienone
+
NAD(P)H
+
H+

Synonyms

IDOLDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.386 ipsdienol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.386 - ipsdienol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(4R)-ipsdienol + NAD(P)+
ipsdienone + NAD(P)H + H+
show the reaction diagram
the enzyme is involved in pheromon production
-
-
?
(4R)-ipsdienol + NAD+
ipsdienone + NADH + H+
show the reaction diagram
no activity with (4S)-ipsdienol. The enzyme shows similar specific activities with NAD+ and NADP+
-
-
?
(4R)-ipsdienol + NADP+
ipsdienone + NADPH + H+
show the reaction diagram
no activity with (4S)-ipsdienol. The enzyme shows similar specific activities with NAD+ and NADP+
-
-
?
(R)-ipsdienol + NADP+
ipsdienone + NADPH + H+
show the reaction diagram
ipsdienone + NADPH + H+
(R)-ipsdienol + NADP+
show the reaction diagram
-
stereospecific reaction
-
-
r
ipsenone + NADPH + H+
racemic ipsenol + NADP+
show the reaction diagram
-
-
-
-
r
racemic ipsenol + NADP+
ipsenone + NADPH + H+
show the reaction diagram
-
-
-
-
r
additional information
?
-
-
the enzyme stereospecifically reduces both ketones to their corresponding (R)-alcohols. Low activity with (R)-menthone, 3-penten-2-ol, 17beta-estradiol, poor or no activity with (S)-ipsdienol, nerol, geraniol, myrcene, citral, 4-methyl-3-penten-2-one, 4-methyl-2-pentanone, 4-methyl-2-pentanol, acetone, 1,3-butendiol, etanol, 2-propanol, 3-hydroxybutyrate, and 2-oxobutyrate, substrate specificity, overview. Product identification by GC-MS analysis
-
-
-