1.1.1.393: 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about 3beta-hydroxycholanate 3-dehydrogenase (NADP+), go to the full flat file.
Reaction
Synonyms
3beta-HSDH, 3beta-hydroxysteroid dehydrogenase, 3beta-hyoxysteroid dehydrogenase
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.393 - 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
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isolithocholate:NADP+ 3-oxidoreductase
This bacterial enzyme is involved, along with EC 1.1.1.52, 3alpha-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3alpha-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3beta-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391, 3beta-hydroxycholanate 3-dehydrogenase (NAD+).