1.1.1.394: aurachin B dehydrogenase
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For detailed information about aurachin B dehydrogenase, go to the full flat file.
Reaction
Synonyms
AuaH
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.394 - aurachin B dehydrogenase
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aurachin B:NAD+ 3-oxidoreductase
The enzyme from the bacterium Stigmatella aurantiaca catalyses the final step in the conversion of aurachin C to aurachin B. In vivo the enzyme catalyses the reduction of 4-[(2E,6E)-farnesyl]-4-hydroxy-2-methyl-3-oxo-3,4-dihydroquinoline-1-oxide to form 4-[(2E,6E)-farnesyl]-2-methyl-1-oxo-3,4-dihydroquinoline-3,4-diol (note that the reactions written above proceed from right to left), which then undergoes a spontaneous dehydration to form aurachin B.