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Requires Zn2+. The enzyme, characterized in bacteria, is specific for NADP. It is part of the synthesis pathway of CDP-ribitol. In Haemophilus influenzae it is part of a multifunctional enzyme also catalysing EC 220.127.116.11, D-ribitol-5-phosphate cytidylyltransferase. cf. EC 18.104.22.168, ribitol-5-phosphate 2-dehydrogenase.