1.1.1.405: ribitol-5-phosphate 2-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about ribitol-5-phosphate 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

D-ribitol 5-phosphate
+
NADP+
=
D-ribulose 5-phosphate
+
NADPH
+
H+

Synonyms

ACS1, Bcs1, bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase, ribulose-5-P reductase, ribulose-5-phosphate reductase, TarIJ, TarJ

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)

Systematic Name

Systematic Name on EC 1.1.1.405 - ribitol-5-phosphate 2-dehydrogenase (NADP+)

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SYSTEMATIC NAME
IUBMB Comments
D-ribitol-5-phosphate:NADP+ 2-oxidoreductase
Requires Zn2+. The enzyme, characterized in bacteria, is specific for NADP. It is part of the synthesis pathway of CDP-ribitol. In Haemophilus influenzae it is part of a multifunctional enzyme also catalysing EC 2.7.7.40, D-ribitol-5-phosphate cytidylyltransferase. cf. EC 1.1.1.137, ribitol-5-phosphate 2-dehydrogenase.