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1.1.1.415: noscapine synthase

This is an abbreviated version!
For detailed information about noscapine synthase, go to the full flat file.

Reaction

narcotine hemiacetal
+
NAD+
=
noscapine
+
NADH
+
H+

Synonyms

NOS, SDR1, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.415 noscapine synthase

Reference

Reference on EC 1.1.1.415 - noscapine synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chen, X.; Facchini, P.J.
Short-chain dehydrogenase/reductase catalyzing the final step of noscapine biosynthesis is localized to laticifers in opium poppy
Plant J.
77
173-184
2014
Papaver somniferum (I3PLR3), Papaver somniferum
Manually annotated by BRENDA team
Li, Y.; Li, S.; Thodey, K.; Trenchard, I.; Cravens, A.; Smolke, C.
Complete biosynthesis of noscapine and halogenated alkaloids in yeast
Proc. Natl. Acad. Sci. USA
115
E3922-E3931
2018
Papaver somniferum (I3PLR3)
Manually annotated by BRENDA team