1.1.1.415: noscapine synthase

This is an abbreviated version!
For detailed information about noscapine synthase, go to the full flat file.

Reaction

Synonyms

NOS, SDR1, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.415 noscapine synthase

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Results	in table
1	AA Sequence
1	Application
2	Cloned(Commentary)
1	Cofactor
2	General Information
4	kcat/KM [mM/s]
4	KM Value [mM]
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
4	Pathway
1	Purification (Commentary)
1	Reaction
2	Reference
5	Source Tissue
6	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.1.1.415 - noscapine synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

narcotine hemiacetal + NAD+

noscapine + NADH + H+

3 entries

narcotine hemiacetal + NADP+

noscapine + NADPH + H+

Papaver somniferum

I3PLR3

the enzyme exhibits higher catalytic efficiency with NAD+ as the cofactor compared with NADP+

748942

-

-

r

noscapine + NADH + H+

narcotine hemiacetal + NAD+

Papaver somniferum

I3PLR3

-

748942

-

-

r

noscapine + NADPH + H+

narcotine hemiacetal + NADP+

Papaver somniferum

I3PLR3

-

748942

-

-

r

narcotine hemiacetal + NAD+

noscapine + NADH + H+

Papaver somniferum

I3PLR3

-

749191

-

-

?

narcotine hemiacetal + NAD+

noscapine + NADH + H+

Papaver somniferum

I3PLR3

the enzyme catalyses the last step in the biosynthesis of the isoquinoline alkaloid noscapine

748942

-

-

?

narcotine hemiacetal + NAD+

noscapine + NADH + H+

Papaver somniferum

I3PLR3

the enzyme exhibits higher catalytic efficiency with NAD+ as the cofactor compared with NADP+

748942

-

-

r