1.1.1.51: 3(or 17)beta-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 3(or 17)beta-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.51

Reaction

testosterone
+
NAD(P)+
=
androstenedione
+
NAD(P)H
+
H+

Synonyms

17 beta-HSD3, 17 beta-hydroxysteroid dehydrogenase, 17-beta-HSD, 17-ketoreductase, 17beta-HSD, 17beta-HSD (type 1), 17beta-HSD (type 3), 17beta-HSD type 2, 17beta-HSD type 3, 17beta-HSD type II, 17beta-HSD-3, 17beta-HSD1, 17beta-HSD2, 17beta-HSD3, 17beta-HSD5, 17beta-HSD7_2, 17beta-HSOR, 17beta-hydroxy steroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase 2, 17beta-hydroxysteroid dehydrogenase type 1, 17beta-hydroxysteroid dehydrogenase type 3, 17beta-hydroxysteroid dehydrogenases, 17beta-hydroxysteroid dehydrogenases type 2, 17beta-hydroxysteroid oxidoreductase, 17beta-hydroxysteroid: NADP 17-oxidoreductase, 17betaHSD2, 3 beta-hydroxysteroid dehydrogenase, 3,17beta-HSD, 3,17beta-hydroxysteroid dehydrogenase, 3-beta HSD, 3beta,17beta-hydroxysteroid dehydrogenase, 3beta-HSD, 3beta-HSD (type 1), 3beta-HSD type-I, 3beta-HSD type-II, 3beta-HSD/isomerase, 3beta-hydroxy steroid dehydrogenase, 3beta-hydroxy-steroid dehydrogenase/DELTA5-DELTA4 isomerase, 3beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase/DELTA5-4-isomerase, 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase, 3beta-hydroxysteroid dehydrogenase/isomerase, 3beta-hydroxystroid oxidoreductase, 3beta/17beta-HSD, 3beta/17beta-hydroxysteroid dehydrogenase, 3beta17betaHSDH, 3betaHSD, AKR1C3, AKR1C35, aldo keto reductase 1C3, beta-hydroxy steroid dehydrogenase, betahsd, dehydrogenase, 17beta-hydroxy steroid, dehydrogenase, 3beta-hydroxy steroid, dehydrogenase, beta-hydroxy steroid, DELTA5-3beta-HSD, DELTA5-3beta-hydroxysteroid dehydrogenase, form 2 type 7 17beta-hydroxysteroid dehydrogenase, HSD, HSD17B1, HSD17B3, LOC101842245, More, pQ3 beta HSD, RDH11, Rdh11/12-like 1, Rdh11/12-like 2, Rdh11/12-like 3, retinol dehydrogenases 11-like, steroid 17beta-reductase, type 17beta-HSD, type 2 17beta-HSD, type 3 17beta-HSD, type 3 17beta-hydroxysteroid dehydrogenase, type 5 17-beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.51 - 3(or 17)beta-hydroxysteroid dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.78
(R)-1,2,3,4-tetrahydro-1-naphthol
pH 7.4, 25°C, recombinant enzyme
16.67
(S)-1,2,3,4-tetrahydro-1-naphthol
pH 7.4, 25°C, recombinant enzyme
23.3
(S)-1-indanol
pH 7.4, 25°C, recombinant enzyme
0.95
1-Acenaphthenol
pH 7.4, 25°C, recombinant enzyme
116.7
17beta-estradiol
pH 7.4, 25°C, recombinant enzyme
1.55
2-Cyclohexen-1-ol
pH 7.4, 25°C, recombinant enzyme
63.33
3beta-hydroxyprogesterone
pH 7.4, 25°C, recombinant enzyme
5.5
4-androstene-3alpha,17beta-diol
pH 7.4, 25°C, recombinant enzyme
9.67
5-androstene-3beta,17beta-diol
pH 7.4, 25°C, recombinant enzyme
10.67
5alpha-Androstan-3beta-ol-17-one
pH 7.4, 25°C, recombinant enzyme
2.83
5alpha-dihydrotestosterone
pH 7.4, 25°C, recombinant enzyme
3.33
5alpha-pregnan-3beta-ol-20-one
pH 7.4, 25°C, recombinant enzyme
0.47
5beta-androstan-3beta-ol-17-one
pH 7.4, 25°C, recombinant enzyme
3
5beta-androstane-3alpha,17beta-diol
pH 7.4, 25°C, recombinant enzyme
2.5
5beta-androstane-3beta,17beta-diol
pH 7.4, 25°C, recombinant enzyme
0.6
5beta-dihydrotestosterone
pH 7.4, 25°C, recombinant enzyme
0.28
5beta-pregnan-3beta,21-diol-20-one
pH 7.4, 25°C, recombinant enzyme
0.42
5beta-Pregnan-3beta-ol-20-one
pH 7.4, 25°C, recombinant enzyme
1.3
alpha-3-hydroxyhexobarbital
pH 7.4, 25°C, recombinant enzyme
0.63
beta-3-hydroxyhexobarbital
pH 7.4, 25°C, recombinant enzyme
21.67
beta-ionol
pH 7.4, 25°C, recombinant enzyme
2.5
cis-benzene dihydrodiol
pH 7.4, 25°C, recombinant enzyme
0.117
Cyclohexanol
pH 7.4, 25°C, recombinant enzyme
2.33
dehydroepiandrosterone
pH 7.4, 25°C, recombinant enzyme
14.17
farnesol
pH 7.4, 25°C, recombinant enzyme
5.67
geraniol
pH 7.4, 25°C, recombinant enzyme
7.67
geranylgeraniol
pH 7.4, 25°C, recombinant enzyme
5
NAD+
pH 7.4, 25°C, with substrate S-tetralol
6
NADH
pH 7.4, 25°C, with substrate S-camphorquinone
0.063
NADP+
pH 7.4, 25°C, with substrate S-camphorquinone
2.17
nerol
pH 7.4, 25°C, recombinant enzyme
3.5
testosterone
pH 7.4, 25°C, recombinant enzyme
3
trans-benzene dihydrodiol
pH 7.4, 25°C, recombinant enzyme