188.8.131.52: 3alpha(or 20beta)-hydroxysteroid dehydrogenase
This is an abbreviated version!
For detailed information about 3alpha(or 20beta)-hydroxysteroid dehydrogenase, go to the full flat file. Reaction
NAD + +
NADH H+ Synonyms
(R)-20-hydroxysteroid dehydrogenase, 20-hydroxysteroid dehydrogenase, 20beta-HSD, 20beta-HSD type 2, 20beta-hydroxysteroid dehydrogenase, 20HSD, 3-alpha hydroxysteroid dehydrogenase type 3, 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase, 3alpha-HSD/CR, 3alpha-HSD3, 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase, carbonyl reductase-like 20beta-HSD, carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase, carbonyl reductase/20beta-hydroxysteroid dehydrogenase A, carbonyl reductase/20beta-hydroxysteroid dehydrogenase B, cortisone reductase, CR/20beta-HSD, CR/20beta-HSD A, CR/20beta-HSD B, dehydrogenase, 20beta-hydroxy steroid, delta4-3-ketosteroid hydrogenase, NADH-20beta-hydroxysteroid dehydrogenase
Source Tissue on EC 184.108.40.206 - 3alpha(or 20beta)-hydroxysteroid dehydrogenase
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287083, 287085, 287086, 287087, 287088, 287089, 287090, 287091, 287092, 287093, 287094
expression appears to be constitutive. No significant difference is noticed in the level of expression among follicles of different stages. Treatment of cultured ovarian follicle cells with gonadotropin and activin has little effect on the expression of the enzyme
expressed in follicle cells
expression in ovarian follicles is low from day 0 to day 8 after spawning and is not detectable on day 11. Distinct expression is evident at day 14, the day of spawning
non-flagellated germ cells and sperm cells
expressed continually in matire testes but not in immature testes of 30-day-old fish
in adult tissues, isoform 20beta-HSD type 2 shows a ubiquitous expression pattern with some minor sex-specific differences
low expression in testis, muscle, intestine, and liver