1.1.1.6: glycerol dehydrogenase

This is an abbreviated version!
For detailed information about glycerol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.6

Reaction

glycerol
+
NAD+
=
Glycerone
+
NADH
+
H+

Synonyms

CglD, dehydrogenase, glycerol, GDH, GDH2, GLD, GldA, GLDH , GlhA, glycerin dehydrogenase, glycerol dehydrogenase, glycerol NAD 2-oxidoreductase, glycerol:NAD+ 2-oxidoreductase, GlyDH, Gro dehydrogenase, GroDHase, gycerol dehydrogenase, NAD+-dependent glycerol dehydrogenase, NAD-linked glycerol dehydrogenase, NAD-specific glycerol dehydrogenase, TmGlyDH, TTHADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.6 glycerol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.6 - glycerol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3R)-2,3-butanediol + NAD+
(3R)-acetoin + NADH
show the reaction diagram
(2R,3R)-2,3-butanediol + NAD+
? + NADH
show the reaction diagram
(R)-1,2-propanediol + NAD+
? + NADH
show the reaction diagram
(R)-1,2-propanediol + NAD+
hydroxyacetone + NADH
show the reaction diagram
1,2,3-butanetriol + NAD+
1,3-dihydroxybutane-2-one + NADH
show the reaction diagram
-
-
-
?
1,2-butanediol + NAD+
1-hydroxybutane-2-one + NADH
show the reaction diagram
-
-
-
r
1,2-butanediol + NAD+
? + NADH
show the reaction diagram
1,2-propanediol + NAD+
hydroxyacetone + NADH
show the reaction diagram
1,3-butanediol + NAD+
4-hydroxy-2-butanone + NADH + H+
show the reaction diagram
1,3-butanediol + NAD+
?
show the reaction diagram
-
relative activity is 6.5% compared to oxidation of glycerol
-
-
?
1,3-dichloro-2-propanol + NAD+
1,3-dichloro-2-propanone + NADH
show the reaction diagram
1,3-propanediol + NAD+
?
show the reaction diagram
1,4-butanediol + NAD+
?
show the reaction diagram
1,4-butanediol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
1-butanol + NAD+
butanal + NADH + H+
show the reaction diagram
1-chloro-2,3-propanediol + NAD+
?
show the reaction diagram
1-octanol + NAD+
octanal + NADH + H+
show the reaction diagram
1-phenylethan-1,2-diol + NAD+
? + NADH
show the reaction diagram
-
-
-
-
?
1-phenylethanol + NAD+
acetophenone + NADH + H+
show the reaction diagram
-
-
-
-
?
1-propanol + NAD+
propanal + NADH + H+
show the reaction diagram
2,3-butanediol + NAD+
3-hydroxybutane-2-one + NADH
show the reaction diagram
2-butanol + NAD+
2-butanone + NADH + H+
show the reaction diagram
2-propanol + NAD+
acetone + NADH + H+
show the reaction diagram
3-amino-1,2-propanediol + NAD+
?
show the reaction diagram
-
104% of the activity with glycerol
-
-
?
3-bromo-1,2-propanediol + NAD+
?
show the reaction diagram
-
109% of the activity with glycerol
-
-
?
3-chloro-1,2-propanediol + NAD+
?
show the reaction diagram
-
130% of the activity with glycerol
-
-
?
3-hydroxypropionaldehyde + NADH
propan-1,3-diol + NAD+
show the reaction diagram
-
-
-
-
?
3-mercapto-1,2-propanediol + NAD+
?
show the reaction diagram
-
155% of the activity with glycerol
-
-
?
acetaldehyde + NADH + H+
ethanol + NAD+
show the reaction diagram
acetoin + NADH + H+
2,3-butanediol + NAD+
show the reaction diagram
benzyl alcohol + NAD+
benzaldehyde + NADH + H+
show the reaction diagram
-
-
-
-
?
beta-glycerophosphate + NAD+
?
show the reaction diagram
-
relative activity is 2% compared to oxidation of glycerol
-
-
?
butane-1,3-diol + NAD+
? + NADH
show the reaction diagram
-
-
-
-
?
D-glyceraldehyde + NADH + H+
glycerol + NAD+
show the reaction diagram
-
-
-
-
r
diglycerol + NAD+
?
show the reaction diagram
-
relative activity is 21% compared to oxidation of glycerol
-
-
?
DL-alpha-glycerophosphate + NAD+
?
show the reaction diagram
DL-glyceraldehyde + NAD+
3-hydroxypyruvaldehyde + NADH
show the reaction diagram
DL-glyceraldehyde + NADH
glycerol + NAD+
show the reaction diagram
erythrite + NAD+
?
show the reaction diagram
-
-
-
-
?
ethanediol + NAD+
glycolaldehyde + NADH
show the reaction diagram
ethanol + NAD+
acetaldehyde + NADH
show the reaction diagram
-
relative activity is 1% compared to oxidation of glycerol
-
-
?
ethanol + NAD+
acetaldehyde + NADH + H+
show the reaction diagram
-
-
-
-
?
ethylene glycol + NAD+
?
show the reaction diagram
ethylene glycol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
glycerol + NAD+
D-glyceraldehyde + NADH
show the reaction diagram
glycerol + NAD+
D-glyceraldehyde + NADH + H+
show the reaction diagram
-
no activity with NADP+. The enzyme shows much higher activity towards glycerol as compared to short chain primary and secondary alcohols. The thermostable enzyme is highly stereospecific in oxidation of glycerol and converts glycerol into D-glyceraldehyde
-
-
r
glycerol + NAD+
dihydroxyacetone + NADH
show the reaction diagram
glycerol + NAD+
dihydroxyacetone + NADH + H+
show the reaction diagram
glycerol + NAD+
glycerone + NADH
show the reaction diagram
-
-
-
-
?
glycerol + NAD+
glycerone + NADH + H+
show the reaction diagram
glycerol + NADP+
glyceraldehyde + NADPH + H+
show the reaction diagram
glycerol-alpha-monochlorohydrin + NAD+
?
show the reaction diagram
glycerol-alpha-monomethyl ether + NAD+
?
show the reaction diagram
glycerone + NADH + H+
glycerol + NAD+
show the reaction diagram
hydroxy-2-propanone + NADH
propylene glycol + NAD+
show the reaction diagram
-
relative activity is 27% compared to oxidation of glycerol
-
-
?
i-inositol + NAD+
?
show the reaction diagram
-
relative activity is 18% compared to oxidation of glycerol
-
-
?
isopropanol + NAD+
acetone + NADH
show the reaction diagram
-
relative activity is 17% compared to oxidation of glycerol
-
-
?
meso-2,3-butanediol + NAD+
(3S)-acetoin + NADH
show the reaction diagram
methylglyoxal + NADH
lactaldehyde + NAD+
show the reaction diagram
N-butyraldehyde + NADH
1-butanol + NAD+
show the reaction diagram
-
-
-
-
?
propane-1,2-diol + NAD+
propane-1-ol-2-one + NADH
show the reaction diagram
-
-
-
-
?
propionaldehyde + NADH
1-propanol + NAD+
show the reaction diagram
-
-
-
-
?
R-1-amino-2-propanol + NAD+
?
show the reaction diagram
-
33% of the activity with glycerol
-
-
?
S-1-amino-2-propanol + NAD+
?
show the reaction diagram
-
9% of the activity with glycerol
-
-
?
sorbitol + NAD+
?
show the reaction diagram
-
relative activity is 3% compared to oxidation of glycerol
-
-
?
additional information
?
-