1.1.1.71: alcohol dehydrogenase [NAD(P)+]
This is an abbreviated version!
For detailed information about alcohol dehydrogenase [NAD(P)+], go to the full flat file.
Word Map on EC 1.1.1.71
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1.1.1.71
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retinoids
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thermoanaerobacter
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all-trans-retinaldehyde
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retinyl
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ethanolicus
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all-trans-retinol
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r-1-phenylethanol
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cyp26a1
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akr1b10
- 1.1.1.71
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retinoids
- thermoanaerobacter
- all-trans-retinaldehyde
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retinyl
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ethanolicus
- all-trans-retinol
-
r-1-phenylethanol
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cyp26a1
- akr1b10
Reaction
Synonyms
ADH, ADH12, ADH2, Adh319, AdhA, AdhE, alcohol dehydrogenase, aldehyde reductase (NADPH/NADH), DHRS3, HvADH2, HVO_B0071, NAD(P)+-dependent alcohol dehydrogenase, NAD(P)H-dependent ADH, NAD(P)H-dependent aldehyde reductase, NADPH-dependent ADHA, NADPH-dependent alcohol dehydrogenase, PH0743, PhADH, RADH, retinal reductase, retinal short-chain dehydrogenase/reductase member 3, retinaldehyde reductase, Retinol dehydrogenase, retinol-active alcohol dehydrogenase, retSDR1, TeSADH, TsAdh319, Tsib_0319, VNG_2617G, YqhD
ECTree
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Organic Solvent Stability
Organic Solvent Stability on EC 1.1.1.71 - alcohol dehydrogenase [NAD(P)+]
for references in articles please use BRENDA:EC1.1.1.71
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2-propanol
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
Acetone
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
acetonitrile
dimethyl sulfoxide
dimethylfluoride
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
DMSO
Ethanol
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
ethylacetate
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high activity (90% of the activity without solvents) is observed in the presence of 50% (v/v)
Glycerol
hexane
Methanol
octane
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high activity (90% of the activity without solvents) is observed in the presence of 50% (v/v)
octanol
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high activity (90% of the activity without solvents) is observed in the presence of 50% (v/v)
tetrahydrofuran
10%, enzyme retains 69% of activity following incubation
acetonitrile
24 h at 4°C, 13% loss of activity at 5% (v/v), 10% loss of activity at 10% (v/v), complete loss of activity at 30% (v/v)
acetonitrile
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24 h at 4°C, 13% loss of activity at 5% (v/v), 10% loss of activity at 10% (v/v), complete loss of activity at 30% (v/v)
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acetonitrile
4°C, 72 h, retains 65% of its original activity following incubation with 5% (v/v) acetonitrile, retains 63% of its original activity following incubation with 10 (v/v) acetonitrile, complete inactivation following incubation with 30 (v/v) dimethyl sulfoxide
acetonitrile
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4°C, 72 h, retains 65% of its original activity following incubation with 5% (v/v) acetonitrile, retains 63% of its original activity following incubation with 10 (v/v) acetonitrile, complete inactivation following incubation with 30 (v/v) dimethyl sulfoxide
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10%, enzyme retains 78% of activity following incubation
dimethyl sulfoxide
24 h at 4°C, 11% loss of activity at 5% (v/v), 9% loss of activity at 10% (v/v), 59% loss of activity at 30% (v/v)
dimethyl sulfoxide
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24 h at 4°C, 11% loss of activity at 5% (v/v), 9% loss of activity at 10% (v/v), 59% loss of activity at 30% (v/v)
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dimethyl sulfoxide
4°C, 72 h, retains 74% of its original activity following incubation with 5% (v/v) dimethyl sulfoxide, retains 69% of its original activity following incubation with 10 (v/v) dimethyl sulfoxide, retains 47% of its original activity following incubation with 30 (v/v) dimethyl sulfoxide
dimethyl sulfoxide
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4°C, 72 h, retains 74% of its original activity following incubation with 5% (v/v) dimethyl sulfoxide, retains 69% of its original activity following incubation with 10 (v/v) dimethyl sulfoxide, retains 47% of its original activity following incubation with 30 (v/v) dimethyl sulfoxide
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DMSO
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
stabilizing and cryoprotecting additive for the preservation of the enzyme over a short-time period, 10 days
Glycerol
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stabilizing and cryoprotecting additive for the preservation of the enzyme over a short-time period, 10 days
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in asymmetric reduction by TeSADH in pure hexane, the organic solvent makes the process more efficient by allowing high concentrations of substrates to be used
hexane
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high activity (90% of the activity without solvents) is observed in the presence of 50% (v/v)
24 h at 4°C, 8% loss of activity at 5% (v/v), 15% loss of activity at 10% (v/v), 94% loss of activity at 30% (v/v)
Methanol
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24 h at 4°C, 8% loss of activity at 5% (v/v), 15% loss of activity at 10% (v/v), 94% loss of activity at 30% (v/v)
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Methanol
4°C, 72 h, retains 70% of its original activity following incubation with 5% (v/v) acetonitrile, retains 67% of its original activity following incubation with 10 (v/v) acetonitrile, retains 39% of its original activity following incubation with 30 (v/v) dimethyl sulfoxide
Methanol
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4°C, 72 h, retains 70% of its original activity following incubation with 5% (v/v) acetonitrile, retains 67% of its original activity following incubation with 10 (v/v) acetonitrile, retains 39% of its original activity following incubation with 30 (v/v) dimethyl sulfoxide
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Methanol
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high activity (90% of the activity without solvents) is observed in the presence of 20% (v/v)
tetrahydrofuran
24 h at 4°C, 37% loss of activity at 5% (v/v), 57% loss of activity at 10% (v/v), complete loss of activity at 30% (v/v)
tetrahydrofuran
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24 h at 4°C, 37% loss of activity at 5% (v/v), 57% loss of activity at 10% (v/v), complete loss of activity at 30% (v/v)
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