1.1.1.75: (R)-aminopropanol dehydrogenase
This is an abbreviated version!
For detailed information about (R)-aminopropanol dehydrogenase, go to the full flat file.
Reaction
Synonyms
1-aminopropan-2-ol-dehydrogenase, 1-aminopropan-2-ol-NAD+ dehydrogenase, AADH, DL-1-aminopropan-2-ol: NAD+ dehydrogenase, L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase, L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase, L-1-amino-2-propanol dehydrogenase, L-aminopropanol dehydrogenase
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Substrates Products
Substrates Products on EC 1.1.1.75 - (R)-aminopropanol dehydrogenase
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REACTION DIAGRAM
1-amino-3-diethylaminopropan-2-ol + NAD+
2-amino-N,N-diethylacetamide + NADH
-
-
-
-
?
2-aminocyclohexanol + NADP+
2-aminocyclohexanone + NADPH + H+
-
-
-
?
D,L-2-hydroxy-2-phenylethylamine + NAD+
2-amino-1-phenylethanone + NADH
-
-
-
-
?
D,L-4-amino-3-hydroxybutyrate + NAD+
4-amino-3-oxobutyrate + NADH
-
-
-
-
?
hydroxyacetone + NAD+
2-oxopropanal + NADH
-
no activity with acetone
-
-
?
aminoacetone + NADH
-
D-enantiomer 50% of activity with L-enantiomer
-
ir
D,L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
more active with L-enantiomer, activity with D-enantiomer might be due to D-aminopropanol specific enzyme
-
?
D,L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
more active with L-enantiomer, activity with D-enantiomer might be due to D-aminopropanol specific enzyme
-
?
D,L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
at high substrate concentrations both enantiomers utilized at the same rate, at low substrate concentration L-enantiomer preferred over D-enantiomer
-
?
1-amino-2-butanone + NADPH + H+
-
-
-
?
L-1-amino-2-butanol + NADP+
1-amino-2-butanone + NADPH + H+
-
-
-
?
aminoacetone + NADPH + H+
-
-
-
?
L-1-amino-2-propanol + NADP+
aminoacetone + NADPH + H+
-
-
-
?
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
involved in L-threonine and vitamin B12 pathway
-
?
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
involved in L-threonine and vitamin B12 pathway
-
?
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
no activity with D-enantiomer
-
r
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
no activity with D-enantiomer
-
r
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
no activity with D-enantiomer
-
r
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
involved in L-threonine and vitamin B12 pathway
-
r
L-1-aminopropan-2-ol + NAD+
aminoacetone + NADH
-
possible role in carnitine metabolism
-
?
L-1-aminopropan-2-ol + NADP+
aminoacetone + NADPH
-
about the same activity as with NAD+ as cofactor
-
r
L-1-aminopropan-2-ol + NADP+
aminoacetone + NADPH
-
half maximum activity
-
?
?
-
the enzyme catalyzes the stereospecific dehydrogenation of several aminoalcohols and also catalyzes the NADPH-dependent asymmetric reduction of (S)-1-phenyl-2-methylaminopropan-1-one to d-psi-EP
-
-
?
additional information
?
-
substrate specificity of AADH and optimization of the catalytic reaction assay method, overview
-
-
?
additional information
?
-
the enzyme catalyzes the stereospecific dehydrogenation of several aminoalcohols and also catalyzes the NADPH-dependent asymmetric reduction of (S)-1-phenyl-2-methylaminopropan-1-one to d-psi-EP
-
-
?
additional information
?
-
substrate specificity of AADH and optimization of the catalytic reaction assay method, overview
-
-
?