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1.1.1.B20: meso-2,3-butandiol dehydrogenase

This is an abbreviated version!
For detailed information about meso-2,3-butandiol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.B20

Reaction

(2R,3S)-butane-2,3-diol
+
NAD+
=
acetoin
+
NADH
+
H+

Synonyms

(2R,3R)-2,3-butanediol dehydrogenase, 2,3-BD dehydrogenase, 2,3-butanediol dehydrogenase, 2,3-butanediol dehydrogenases, ADH-9, ARA1, BDH, BdhA, BS-BDH, BtBDH, budC, butACg, butanediol dehydrogenase, ButB, CG-BDH, Cgl2674, mbdh, meso-2,3-BD dehydrogenase, meso-2,3-BDH, meso-2,3-butanediol dehydrogenase, meso-acetoin reductase, meso-BD, meso-BDH, MF996569, More, NAD(H)-dependent meso-2,3-BDH, NAD(H)-dependent meso-2,3-butanediol dehydrogenase, PA4153, PB24_3312, PF-BDH, PF1960, PT-BDH, R,R-2,3-butanediol dehydrogenase/meso-2,3-butanediol dehydrogenase/diacetyl reductase, SmBdh

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B20 meso-2,3-butandiol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.B20 - meso-2,3-butandiol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3R)-butane-2,3-diol + NAD+
(3R)-acetoin + NADH + H+
show the reaction diagram
-
-
-
r
(2R,3S)-butane-2,3-diol + NAD+
(3R)-acetoin + NADH + H+
show the reaction diagram
(2R,3S)-butane-2,3-diol + NAD+
(3S)-acetoin + NADH + H+
show the reaction diagram
(2R,3S)-butane-2,3-diol + NAD+
acetoin + NADH + H+
show the reaction diagram
(2S,3S)-2,3-butanediol + NAD+
(3S)-acetoin + NADH
show the reaction diagram
-
(2S,3S)-2,3-butanediol is a poor substrate
-
-
?
(2S,3S)-2,3-butanediol + NAD+
(3S)-acetoin + NADH + H+
show the reaction diagram
(2S,3S)-butane-2,3-diol + NAD+
(S)-acetoin + NADH + H+
show the reaction diagram
(3R)-acetoin + NADH + H+
(2R,3S)-butane-2,3-diol + NAD+
show the reaction diagram
(3R)-acetoin + NADH + H+
meso-2,3-butanediol + NAD+
show the reaction diagram
(3S)-acetoin + NADH + H+
(2S,3S)-2,3-butanediol + NAD+
show the reaction diagram
(R)-acetoin + NADH + H+
meso-2,3-butanediol + NAD+
show the reaction diagram
(R)-acetoin + NADPH + H+
meso-2,3-butanediol + NADP+
show the reaction diagram
(R,R)-butane-2,3-diol + NAD+
(3R)-acetoin + NADH + H+
show the reaction diagram
stereoselective interconversion
-
-
r
(R,R)-butane-2,3-diol + NAD+
(R)-acetoin + NADH + H+
show the reaction diagram
-
-
-
r
(S)-acetoin + NADH + H+
meso-2,3-butanediol + NAD+
show the reaction diagram
-
-
-
-
r
1,2-cyclohexanedione + NADH + H+
(S,S)-1,2-cyclohexanediol + NAD+
show the reaction diagram
1,2-pentanediol + NADH + H+
?
show the reaction diagram
1,2-propandiol + NADH + H+
?
show the reaction diagram
low activity
-
-
?
1-hydroxy-2-butanone + NADH + H+
? + NAD+
show the reaction diagram
-
-
-
?
1-phenyl-1,2-propanedione + NADH + H+
(S)-2-hydroxy-1-phenylpropan-1-one + NAD+
show the reaction diagram
2 (R,S)-acetoin + 2 NADPH + 2 H+
(2S,3S)-2,3-butanediol + meso-2,3-butanediol + NADP+
show the reaction diagram
-
-
Ara1p is selective toward the acetoin carbonyl group, leading to an S-alcohol
-
r
2 acetoin + 2 NADH + 2 H+
(2S,3S)-2,3-butanediol + meso-2,3-butanediol + 2 NAD+
show the reaction diagram
-
racemic mixture of (3S/3R)-acetoin
-
-
r
2,3-heptanedione + NADH + H+
3-hydroxy-2-heptanone + NAD+
show the reaction diagram
-
-
-
?
2,3-hexanedione + NADH + H+
(S)-3-hydroxy-2-hexanone + NAD+
show the reaction diagram
-
-
-
?
2,3-pentandione + NADH + H+
? + NAD+
show the reaction diagram
-
-
-
?
2,3-pentanedione + NADH + H+
(3S)-3-hydroxy-2-pentanone + NAD+
show the reaction diagram
-
-
-
?
3,4-hexanedione + NADH + H+
(3S,4S)-3,4-hexanediol + NAD+
show the reaction diagram
-
-
-
?
4-methyl-2-pentanone + NADH + H+
4-methyl-2-pentanol + NAD+
show the reaction diagram
acetoin + NADH + H+
(2R,3S)-butane-2,3-diol + NAD+
show the reaction diagram
acetoin + NADH + H+
meso-2,3-butanediol + NAD+
show the reaction diagram
butane-1,2-diol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
?
diacetyl + 2 NADH + 2 H+
(2R,3R)-butane-2,3-diol + 2 NAD+
show the reaction diagram
-
-
-
r
diacetyl + NADH + H+
(3R)-acetoin + NAD+
show the reaction diagram
-
-
-
r
diacetyl + NADH + H+
(3S)-acetoin + NAD+
show the reaction diagram
-
-
-
?
glycerol + NADH + H+
?
show the reaction diagram
low activity
-
-
?
L-acetoin + NADH
L-2,3-butanediol + NAD+
show the reaction diagram
-
-
-
?
meso-2,3-butanediol + NAD+
(3R)-acetoin + NADH + H+
show the reaction diagram
-
-
-
r
meso-2,3-butanediol + NAD+
(R)-acetoin + NADH + H+
show the reaction diagram
meso-2,3-butanediol + NAD+
acetoin + NADH
show the reaction diagram
-
-
-
-
?
meso-2,3-butanediol + NAD+
acetoin + NADH + H+
show the reaction diagram
-
-
-
-
?
meso-2,3-butanediol + NADP+
(R)-acetoin + NADPH + H+
show the reaction diagram
very low activity
-
-
r
propane-1,2-diol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
?
rac acetoin + NADH + H+
(2R,3R)-butane-2,3-diol + NAD+
show the reaction diagram
-
-
-
?
rac acetoin + NADH + H+
(2R,3S)-butane-2,3-diol + NAD+
show the reaction diagram
-
-
-
?
additional information
?
-