1.1.1.B3: (S)-specific secondary alcohol dehydrogenase
This is an abbreviated version!
For detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.
Reaction
Synonyms
(S)-1-phenylethanol dehydrogenase, (S)-1-phenylethanolsynthase, acetophenone reductase, ADH, ADH-A, ADH1, ADH2, ADHTt, APRD, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, NAD+-dependent ADH, PED, S-ADH, SADH, Scr2, SDR, short chain dehydrogenase, short-chain NAD(H)-dependent alcohol dehydrogenase, SOU1, SPES, TtADH
ECTree
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General Information
General Information on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
evolution
metabolism
evolution
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the enzyme belongs to the short-chain dehydrogenase/reductase family
evolution
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the enzyme belongs to the short-chain dehydrogenase/reductase family
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metabolism
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strain EbN1 produces (S)-1-phenylethanol via a direct anaerobic oxidation of ethylbenzene by the molybdenum enzyme ethylbenzene dehydrogenase. In the second step of the pathway, PEDH catalyzes the stereospecific conversion of (S)-1-phenylethanol to acetophenone and is also capable to catalyze the industrially important reverse reaction, namely, NADH-dependent enantioselective reduction of acetophenone to (S)-1-phenylethanol
metabolism
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strain EbN1 produces (S)-1-phenylethanol via a direct anaerobic oxidation of ethylbenzene by the molybdenum enzyme ethylbenzene dehydrogenase. In the second step of the pathway, PEDH catalyzes the stereospecific conversion of (S)-1-phenylethanol to acetophenone and is also capable to catalyze the industrially important reverse reaction, namely, NADH-dependent enantioselective reduction of acetophenone to (S)-1-phenylethanol
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