1.1.1.B3: (S)-specific secondary alcohol dehydrogenase
This is an abbreviated version!
For detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.
Reaction
Synonyms
(S)-1-phenylethanol dehydrogenase, (S)-1-phenylethanolsynthase, acetophenone reductase, ADH, ADH-A, ADH1, ADH2, ADHTt, APRD, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, NAD+-dependent ADH, PED, S-ADH, SADH, Scr2, SDR, short chain dehydrogenase, short-chain NAD(H)-dependent alcohol dehydrogenase, SOU1, SPES, TtADH
ECTree
1.1.1.B3 (S)-specific secondary alcohol dehydrogenaseAdvanced search results
results (
results (Results
in table
6
26
61
11
38
KM Value
KM Value on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
4.2
(S)-1-indanol
-
pH 6.0, 65°C, recombinant enzyme, reduction reaction
5.8
alpha-tetralone
-
pH 6.0, 65°C, recombinant enzyme, reduction reaction
5.1
rac-1-indanol
-
pH 6.0, 65°C, recombinant enzyme, reduction reaction
5.3
rac-alpha-tetralol
-
pH 6.0, 65°C, recombinant enzyme, reduction reaction
0.012
(S)-2-butanol
-
wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65°C
29.8
(S)-2-butanol
-
mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65°C
0.07
(S)-2-pentanol
-
wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65°C
8.8
(S)-2-pentanol
-
mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65°C
additional information
additional information
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kinetics and substrate specificity, overview
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additional information
additional information
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enzyme exhibits positive cooperativity in both forward and reverse direction
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