1.1.2.3: L-lactate dehydrogenase (cytochrome)

This is an abbreviated version!
For detailed information about L-lactate dehydrogenase (cytochrome), go to the full flat file.

Word Map on EC 1.1.2.3

Reaction

(S)-lactate
+ 2 ferricytochrome c =
pyruvate
+ 2 ferrocytochrome c + 2 H+

Synonyms

Cyb2, cytochrome b2, cytochrome c oxido reductase, FC b2, Fcb2, flavocytochrome b, flavocytochrome b2, iLDH, L(+)-lactate:cytochrome c oxidoreductase, L-(+)-lactate ferricytochrome c oxidoreductase, L-lactate cytochrome c oxidoreductase, L-lactate cytochrome c reductase, L-lactate dehydrogenase [Cytochrome], L-lactate ferricytochrome C oxidoreductase, L-lactate-cytochrome c oxidoreductase, L-lactate-cytochrome c-oxidoreductase, L-lactate: cytochrome c oxidoreductase, L-lactate:cytochrome c oxidoreductase, L-lactate:cytochrome c-oxidoreductase, L-LCR, L-LDH (FMN-dependent), lactate dehydrogenase (cytochrome), lactic acid dehydrogenase, lactic cytochrome c reductase, NAD+ - independent LDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.2 With a cytochrome as acceptor
                1.1.2.3 L-lactate dehydrogenase (cytochrome)

Specific Activity

Specific Activity on EC 1.1.2.3 - L-lactate dehydrogenase (cytochrome)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.055
-
(S)-lactate with cytochrome c as electron acceptor
0.4
-
+/- 0.02, was found in the cell-free extract
0.415
-
partially purified enzyme with 2,6-dichloroindophenol as electron acceptor
0.43
-
+/-0.05, cell-free extract
0.51
-
+/- 0.03, cell-free extract
0.66
-
+/- 0.06, the cell-free extract
0.72
-
6-dichloroindophenol as electron acceptor
1.2
-
recombinant overexpressed enzyme in crude cell-free extract, pH 7.8, 30°C
3
-
cell-free extract from recombinant Hansenula polymorpha cell line expressing gene CYB2
3.2
-
recombinant enzyme in cells of Hansenula polymorpha
4.45
-
recombinant overexpressed enzyme in permeabilized cells, pH 7.8, 30°C
9
-
purified native enzyme, pH 7.5, 20°C
11
-
crude enzyme, cell-free extracts, pH 7.8, 20°C
895
-
purified enzyme