Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.3.16: ecdysone oxidase

This is an abbreviated version!
For detailed information about ecdysone oxidase, go to the full flat file.

Word Map on EC 1.1.3.16

Reaction

ecdysone
+
O2
=
3-Dehydroecdysone
+
H2O2

Synonyms

beta-ecdysone oxidase, DmEO, ecdysone oxidase, EO, EO2, oxidase, ecdysone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.16 ecdysone oxidase

General Information

General Information on EC 1.1.3.16 - ecdysone oxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
enzyme deletion extends the duration of the final instar larval stage
metabolism
ecdysone is inactivated to 3-dehydroecdysone under ecdysone oxidase, followed by NAD(P)H-dependent irreversible reduction to 3-epiecdysteroid under 3-dehydroecdysone 3alpha-reductase. On the other hand, 3-dehydroecdysone undergoes reversible reduction to ecdysone by 3-dehydroecdysone 3beta-reductase in the hemolymph
physiological function
-
middle silk gland-specific enzyme overexpression inhibits autophagy in the silk gland