1.1.5.13: (S)-2-hydroxyglutarate dehydrogenase
This is an abbreviated version!
For detailed information about (S)-2-hydroxyglutarate dehydrogenase, go to the full flat file.
Reaction
Synonyms
L-2-HG dehydrogenase, L-2-hydroxyglutarate dehydrogenase, L-2-hydroxyglutarate oxygenase, L-2HG dehydrogenase, L-2HGDH, L2HG dehydrogenase, L2HG:quinone oxidoreductase, L2HGDH, lhgO, YgaF
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 1.1.5.13 - (S)-2-hydroxyglutarate dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
D-2-hydroxyglutarate + 2,6-dichlorophenolindophenol
2-oxoglutarate + reduced 2,6-dichlorophenolindophenol
-
3.7% activity compared to L-2-hydroxyglutarate
-
-
?
L-2-hydroxyglutarate + 2,6-dichlorophenolindophenol
2-oxoglutarate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
L-2-hydroxyglutarate + iodonitrotetrazolium
2-oxoglutarate + reduced iodonitrotetrazolium
-
-
-
-
?
L-2-hydroxyglutarate + menaquinone-4
2-oxoglutarate + menaquinol-4
-
-
-
-
?
L-2-hydroxyglutarate + oxidized o-phenylendiamine
alpha-ketoglutarate + reduced o-phenylendiamine
-
experimental setup
-
-
ir
L-2-hydroxyglutarate + a quinone
2-oxoglutarate + a quinol
-
-
-
-
?
?
-
-
the enzyme is not active in the presence of NAD+, NADP+, cytochrome c or O2. No activity with glycolate, L-lactate or D-lactate
-
-
?
additional information
?
-
-
no activity with dimethylglycine, sarcosine, butyraldehyde or 3-hydroxybutyric acid. Most 2-hydroxy acids are ineffective as substrates, including L-malic acid, DL-malic acid, DL-lactic acid, L-mandelic acid, D-mandelic acid, and 2-hydroxycaproic acid
-
-
?