1.1.9.1: alcohol dehydrogenase (azurin)

This is an abbreviated version, for detailed information about alcohol dehydrogenase (azurin), go to the full flat file.

Reaction

a primary alcohol
+
azurin
=
an aldehyde
+
reduced azurin

Synonyms

ADH IIB, ADH IIG, QH-ADH, quinohaemoprotein alcohol dehydrogenase, quinohemoprotein alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.9 With a copper protein as acceptor
                1.1.9.1 alcohol dehydrogenase (azurin)

Systematic Name

Systematic Name on EC 1.1.9.1 - alcohol dehydrogenase (azurin)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
alcohol:azurin oxidoreductase
A soluble, periplasmic PQQ-containing quinohemoprotein. Also contains a single heme c. Occurs in Comamonas and Pseudomonas. Does not require an amine activator. Oxidizes a wide range of primary and secondary alcohols, and also aldehydes and large substrates such as sterols; methanol is not a substrate. Usually assayed with phenazine methosulfate or ferricyanide. Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed ‘propeller’ structure, a calcium ion bound to the PQQ in the active site and an unusual disulfide ring structure in close proximity to the PQQ.