1.1.98.5: secondary-alcohol dehydrogenase (coenzyme-F420)
This is an abbreviated version!
For detailed information about secondary-alcohol dehydrogenase (coenzyme-F420), go to the full flat file.
Word Map on EC 1.1.98.5
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1.1.98.5
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methanoculleus
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methanogen
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isopropanol
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prochiral
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archaea
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re-face
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ketones
- 1.1.98.5
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methanoculleus
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methanogen
- isopropanol
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prochiral
- archaea
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re-face
- ketones
Reaction
Synonyms
ADF, F420-dependent alcohol dehydrogenase, F420-dependent secondary alcohol dehydrogenase, F420-specific sec-ADH, F420-specific secondary alcohol dehydrogenase, propane-2-ol:F420 oxidoreductase, secondary alcohol:F420 oxidoreductase
ECTree
1.1.98.5 secondary-alcohol dehydrogenase (coenzyme-F420)Advanced search results
results (
results (Substrates Products
Substrates Products on EC 1.1.98.5 - secondary-alcohol dehydrogenase (coenzyme-F420)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-phenylpropan-1-one + reduced coenzyme F420
(S)-1-phenylpropan-1-ol + oxidized coenzyme F420
the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee)
-
-
?
2-pentanone + reduced coenzyme F420
2-pentanol + oxidized coenzyme F420
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-
-
-
r
2-propanol + oxidized coenzyme F420
2-propanone + reduced coenzyme F420
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-
2-propanone i.e. acetone
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r
2-propanol + oxidized coenzyme F420
propanone + reduced coenzyme F420
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-
propanone i.e. acetone
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r
4-methylpentan-2-one + reduced coenzyme F420
(S)-4-methylpentan-2-ol + oxidized coenzyme F420
the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee)
-
-
?
acetophenone + reduced coenzyme F420
(S)-1-phenylethanol + oxidized coenzyme F420
the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee)
-
-
?
cyclopentanol + oxidized coenzyme F420
cyclopentanone + reduced coenzyme F420
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-
-
-
r
cyclopentanone + reduced coenzyme F420
cyclopentanol + oxidized coenzyme F420
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-
-
-
r
methoxyacetone + reduced coenzyme F420
(2S)-1-methoxypropan-2-ol + oxidized coenzyme F420
the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee)
-
-
?
octan-3-one + reduced coenzyme F420
(S)-3-octanol + oxidized coenzyme F420
the (S)-alcohol is obtained in excellent enantiopurity (above 99% ee)
-
-
?
pentan-2-one + reduced coenzyme F420
(S)-2-pentanol + oxidized coenzyme F420
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-
-
?
(R)-2-butanol + oxidized coenzyme F420
2-butanone + reduced coenzyme F420
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-
-
-
r
(R)-2-butanol + oxidized coenzyme F420
2-butanone + reduced coenzyme F420
-
-
-
-
r
(S)-2-butanol + oxidized coenzyme F420
2-butanone + reduced coenzyme F420
-
-
-
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r
(S)-2-butanol + oxidized coenzyme F420
2-butanone + reduced coenzyme F420
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-
-
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r
2-butanone + reduced coenzyme F420
2-butanol + oxidized coenzyme F420
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-
-
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r
2-butanone + reduced coenzyme F420
2-butanol + oxidized coenzyme F420
-
-
-
-
r
2-pentanol + oxidized coenzyme F420
2-pentanone + reduced coenzyme F420
-
-
-
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r
2-pentanol + oxidized coenzyme F420
2-pentanone + reduced coenzyme F420
-
-
-
-
r
propanone + reduced coenzyme F420
2-propanol + oxidized coenzyme F420
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the enzyme is Si-face specific with respect to the C5 atom of coenzyme F420, 2-propanone i.e. acetone
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-
r
propanone + reduced coenzyme F420
2-propanol + oxidized coenzyme F420
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2-propanone i.e. acetone
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-
r
additional information
?
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-
activity with ethanol or 1-propanol at the same concentration is only 0.1% compared to activity with 2-propanol. Acetaldehyde and propionaldehyde are reduced at the same rate as 2-propanone
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-
?
additional information
?
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-
the enzyme catalysed the oxidation of various secondary and cyclic alcohols to the corresponding ketones and the reverse reaction. No primary alcohols are oxidized. 1,3-butandiol, glycerol, methanol, ethanol, 1,2-ethandiol, 1 -propanol, 1-amino-2-propanol, 1-butanol, 1-pentanol, 1-hexanol and benzylalcohol are not oxidized nor are the respective aldehydes or ketones reduced
-
-
?
additional information
?
-
-
the enzyme catalysed the oxidation of various secondary and cyclic alcohols to the corresponding ketones and the reverse reaction. No primary alcohols are oxidized. 1,3-butandiol, glycerol, methanol, ethanol, 1,2-ethandiol, 1 -propanol, 1-amino-2-propanol, 1-butanol, 1-pentanol, 1-hexanol and benzylalcohol are not oxidized nor are the respective aldehydes or ketones reduced
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-
?
