1.1.99.14: glycolate dehydrogenase
This is an abbreviated version!
For detailed information about glycolate dehydrogenase, go to the full flat file.
Word Map on EC 1.1.99.14
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1.1.99.14
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glyoxylate
-
photorespiration
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photorespiratory
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d-lactate
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phosphoglycolate
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glycerate
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microbodies
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hydroxypyruvate
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carboligase
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tartronic
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glcdh
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high-co2-requiring
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14coxalate
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leaf-type
- 1.1.99.14
- glyoxylate
-
photorespiration
-
photorespiratory
- d-lactate
- phosphoglycolate
- glycerate
- microbodies
- hydroxypyruvate
-
carboligase
-
tartronic
- glcdh
-
high-co2-requiring
-
14coxalate
-
leaf-type
Reaction
Synonyms
GADH, GDH, GlcD, GlcD1, GlcD2, GlcDH, glycolate dehydrogenase, glycolate dehydrogenase I, glycolate oxidoreductase, glycolic acid dehydrogenase, More
ECTree
1.1.99.14 glycolate dehydrogenaseAdvanced search results
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1
4100
10
42
18
Substrates Products
Substrates Products on EC 1.1.99.14 - glycolate dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2,6-dichlorophenol-indophenol + acceptor
?
-
DCIP decoloration assay, mitochondrial glycolate oxidation contributes to photorespiration in higher plants
-
-
?
D-lactate + 2,6-dichlorophenolindophenol
?
-
100% activity with D-lactate and 2,6-dichlorophenolindophenol
-
-
?
D-lactate + phenazine methosulfate
?
-
93% activity compared to 2,6-dichlorophenolindophenol
-
-
?
DL-malate + acceptor
2-oxosuccinate + reduced acceptor
-
about 3% activity of glycolate
-
-
?
glycerate 3-phosphate + 2,6-dichlorophenolindophenol
?
-
2.9% activity compared to D-lactate
-
-
?
glycolaldehyde + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
38% activity compared to glycolate
-
-
?
glycolate + 2,6-dichlorophenolindophenol
glyoxylate + reduced 2,6-dichlorophenolindophenol
glycolate + nitro blue tetrazolium
glyoxylate + reduced nitro blue tetrazolium
-
100% activity
-
-
?
L-lactate + 2,6-dichlorophenolindophenol
?
-
12.4% activity compared to D-lactate
-
-
?
L-lactate + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
232% activity compared to glycolate
-
-
?
methyl glycolate + nitro blue tetrazolium
methyl glyoxylate + reduced nitro blue tetrazolium
-
82% activity compared to glycolate
-
-
?
phosphoglycolate + acceptor
? + reduced acceptor
-
about 9% activity of glycolate
-
-
?
succinate + 2,6-dichlorophenolindophenol
?
-
8.5% activity compared to D-lactate
-
-
?
(R)-lactate + acceptor
pyruvate + reduced acceptor
-
artificial acceptor 2,6-dichlorophenolindophenol is reduced via phenazine methosulfate, cytochrome c can replace 2,6-dichlorophenolindophenol
-
-
?
(S)-lactate + acceptor
pyruvate + reduced acceptor
-
about 16% activity of glycolate
-
-
?
dihydroxyacetone + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
162% activity compared to glycolate
-
-
?
dihydroxyacetone + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
162% activity compared to glycolate
-
-
?
DL-glyceraldehyde + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
78% activity compared to glycolate
-
-
?
DL-glyceraldehyde + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
78% activity compared to glycolate
-
-
?
DL-lactate + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
235% activity compared to glycolate
-
-
?
DL-lactate + nitro blue tetrazolium
? + reduced nitro blue tetrazolium
-
235% activity compared to glycolate
-
-
?
glycolate + 2,6-dichlorophenolindophenol
glyoxylate + reduced 2,6-dichlorophenolindophenol
-
71.7% activity compared to D-lactate
-
-
?
glycolate + 2,6-dichlorophenolindophenol
glyoxylate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
r
glycolate + 2,6-dichlorophenolindophenol
glyoxylate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
glycolate + 2,6-dichlorophenolindophenol
glyoxylate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
glycolate + acceptor
glyocylate + reduced acceptor
-
the bacterial enzyme catalyzes phenazine methosulfate dependent reduction of 2,6-dichlorophenolindophenol or cytochrome c
-
-
?
glycolate + acceptor
glyocylate + reduced acceptor
-
in green algae the enzyme is part of glycolate metabolism
-
-
?
glycolate + acceptor
glyocylate + reduced acceptor
-
in green algae the enzyme is part of glycolate metabolism
-
-
?
glycolate + acceptor
glyoxylate + reduced acceptor
-
involved in the photorespiration pathway
-
-
?
glycolate + acceptor
glyoxylate + reduced acceptor
-
artificial acceptor 2,6-dichlorophenolindophenol is reduced via phenazine methosulfate, cytochrome c can replace 2,6-dichlorophenolindophenol
-
?
glycolate + NAD+
glyoxylate + NADH
-
the enzyme is involved in the bacterial 2-phosphoglycolate pathway, overview
-
-
?
glyoxylate + acceptor
oxalate + reduced acceptor
-
about 6% activity of glycolate
-
-
?
glyoxylate + acceptor
oxalate + reduced acceptor
-
2,6-dichlorophenolindophenol as acceptor, no reaction with O2 as acceptor
-
-
?
additional information
?
-
-
no activity with formate, malate, acetate, FAD, FMN, NAD+, NADP+, or cytochrome c
-
-
?
additional information
?
-
-
the enzyme does not require NAD+ and NADP+ as an electron carrier, and primary alcohols, dihydric alcohols and aliphatic aldehydes are not oxidized. Ethanol, 1-propanol, 2-propanol, 1-butanol, ethylene glycol, propylene glycol, 1,3-propanediol, glycerol, glyoxylate, glyoxal, methylglyoxal, acetaldehyde, propylaldehyde, L-malic acid, L-kactic acid, D-malic acid and L-tartaric acid are inert
-
-
?
additional information
?
-
-
the enzyme does not require NAD+ and NADP+ as an electron carrier, and primary alcohols, dihydric alcohols and aliphatic aldehydes are not oxidized. Ethanol, 1-propanol, 2-propanol, 1-butanol, ethylene glycol, propylene glycol, 1,3-propanediol, glycerol, glyoxylate, glyoxal, methylglyoxal, acetaldehyde, propylaldehyde, L-malic acid, L-kactic acid, D-malic acid and L-tartaric acid are inert
-
-
?
