1.1.99.18: cellobiose dehydrogenase (acceptor)

This is an abbreviated version!
For detailed information about cellobiose dehydrogenase (acceptor), go to the full flat file.

Word Map on EC 1.1.99.18

Reaction

cellobiose
+
acceptor
=
cellobiono-1,5-lactone
+
reduced acceptor

Synonyms

cbdA, CBO, CBOR, Cdh, CDH IIA, CDH IIB, cdh-1, CDH1, Cdh2, cellobiose (acceptor) 1-oxidoreductase, cellobiose dehydrogenase, cellobiose oxidase, cellobiose oxidoreductase, cellobiose [acceptor] 1-oxidoreductase, Cellobiose-quinone oxidoreductase, cellobiose:(acceptor) 1-oxidoreductase, cellobiose:quinone oxidoreductase, cellobiose:[acceptor] 1-oxidoreductase, DCHsr, dehydrogenase, cellobiose, MtCDH, oxidase, cellobiose, Thite_59724, TpCDH, TvCDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.18 cellobiose dehydrogenase (acceptor)

pH Optimum

pH Optimum on EC 1.1.99.18 - cellobiose dehydrogenase (acceptor)

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2.7 - 5
-
depends on electron acceptor
3 - 5
-
cellobiose + 2,6-dichlorophenol-indophenol, wild-type enzyme
3
-
cellobiose + cytochrome c, highest activity at pH 3, decreasing as the pH increases, recombinant wild-type enzyme, mutant enzymes N732H, N732Q and N732A
3.5
lactose as substrate, 1,4-benzoquinone or ferricenium or cytochrome c as electron acceptor
3.5 - 4.5
-
acceptor: methylene blue
3.5 - 4.5
-
lactose + cytochrome c, in acetate buffer
4 - 4.5
Monilia sitophila
-
-
4 - 4.5
-
the optimum pH range for direct electron transfer between enzyme and electrode is pH 4.0-4.5
4.5 - 5
-
depending on the electron acceptor
4.5 - 7.5
two activity peaks, one at pH 3.5 and another at pH 4.5-4.75, the activity at pH 3.5 is 90% of the activity at pH 4.5-7.5, reaction with cellobiose and cytochrome c
5 - 6
5.5
-
with 2,6-dichlorophenolindophenol as cosubtrate
5.5 - 7
-
reaction with 2,6-dichlorophenol indophenol
6.5 - 7
-
cellobiose + 2,6-dichlorophenol-indophenol, mutant enzyme N732E and N732D
6.5
-
cyclic voltametry
7 - 9
-
cytochrome c as electron acceptor
7.5
review, different references
8 - 9
-
acceptor: phenazine methosulfate
9
-
ferricyanide as electron acceptor
additional information
-
pH-optima for the oxidation vary remarkably depending on the electron acceptor