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1.1.99.2: L-2-hydroxyglutarate dehydrogenase

This is an abbreviated version!
For detailed information about L-2-hydroxyglutarate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.2

Reaction

(S)-2-hydroxyglutarate
+
acceptor
=
2-oxoglutarate
+
reduced acceptor

Synonyms

2-hydroxyglutarate dehydrogenase, alpha-hydroxyglutarate dehydrogenase, alpha-hydroxyglutarate dehydrogenase (NAD+ specific), alpha-hydroxyglutarate oxidoreductase, alpha-ketoglutarate reductase, dehydrogenase, 2-hydroxyglutarate, hydroxyglutaric dehydrogenase, L-2-HG dehydrogenase, L-2-HGDH, L-2-hydroxyglutarate dehydrogenase, L-2-hydroxyglutaric acid dehydrogenase, L-2HG dehydrogenase, L-2HGDH, L-alpha-hydroxyglutarate dehydrogenase, L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase, L2HGDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.2 L-2-hydroxyglutarate dehydrogenase

Sequence

Sequence on EC 1.1.99.2 - L-2-hydroxyglutarate dehydrogenase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
L2HDH_ACCSB
Accumulibacter sp. (strain BA-93)
388
0
40540
Swiss-Prot
-
L2HDH_ACHAE
369
0
38740
Swiss-Prot
-
L2HDH_ARATH
483
0
53526
Swiss-Prot
other Location (Reliability: 5)
L2HDH_BOVIN
463
0
51022
Swiss-Prot
Mitochondrion (Reliability: 2)
L2HDH_CAEBR
434
0
48359
Swiss-Prot
other Location (Reliability: 5)
L2HDH_CAEEL
433
0
47901
Swiss-Prot
other Location (Reliability: 5)
L2HDH_DICDI
446
0
49908
Swiss-Prot
other Location (Reliability: 3)
L2HDH_HUMAN
463
0
50316
Swiss-Prot
Mitochondrion (Reliability: 1)
L2HDH_INDAL
Indibacter alkaliphilus (strain CCUG 57479 / KCTC 22604 / LW1)
399
0
44131
Swiss-Prot
-
L2HDH_MOUSE
464
0
50899
Swiss-Prot
Mitochondrion (Reliability: 3)
L2HDH_NEMVE
456
0
50175
Swiss-Prot
Mitochondrion (Reliability: 1)
L2HDH_PONAB
419
0
45538
Swiss-Prot
Mitochondrion (Reliability: 2)
A0A0B2QQV7_GLYSO
447
0
49218
TrEMBL
Mitochondrion (Reliability: 3)
A0A6F8PCB5_9PSED
476
0
50188
TrEMBL
-
A0A6J8EGT8_MYTCO
466
0
51837
TrEMBL
Mitochondrion (Reliability: 2)
A0A0A1U537_ENTIV
1068
0
115383
TrEMBL
other Location (Reliability: 4)
G2KUM4_FRUST
Fructilactobacillus sanfranciscensis (strain TMW 1.1304)
339
0
37228
TrEMBL
-
A0A6J4T2D9_9SPHN
471
0
49672
TrEMBL
-
A0A2I0B5I7_9ASPA
423
0
45678
TrEMBL
Mitochondrion (Reliability: 4)
A0A812BVC7_SEPPH
161
1
18480
TrEMBL
Mitochondrion (Reliability: 3)
A0A3G8CBX0_9PSED
473
0
50554
TrEMBL
-
A0A3G8CGF4_9PSED
472
0
51992
TrEMBL
-
A0A1B1JZ64_RHOOP
401
0
42976
TrEMBL
-
A0A098BW45_9NOCA
401
0
42347
TrEMBL
-
B8K5I8_9VIBR
404
0
44761
TrEMBL
-
A0A6J4KL48_9GAMM
uncultured Lysobacter sp
462
0
50054
TrEMBL
-
W6K275_9MICO
398
0
42319
TrEMBL
-
A0A3B0R963_9ZZZZ
180
0
19091
TrEMBL
other Location (Reliability: 2)
B9U227_FUSVA
132
0
14588
TrEMBL
-
Q1LPA0_CUPMC
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
368
0
38866
TrEMBL
-
A9VGL2_BACMK
Bacillus mycoides (strain KBAB4)
400
0
44507
TrEMBL
-
A0A7R8H004_LEPSM
680
3
78394
TrEMBL
Secretory Pathway (Reliability: 1)
B8K737_9VIBR
420
0
46505
TrEMBL
-
B0E8T6_ENTDS
Entamoeba dispar (strain ATCC PRA-260 / SAW760)
244
0
27236
TrEMBL
other Location (Reliability: 4)
A0A840IG52_9ACTN
421
1
44443
TrEMBL
-
A8L1C3_FRASN
Frankia sp. (strain EAN1pec)
427
0
45626
TrEMBL
-
K4R8U7_STRDJ
Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768)
402
0
43106
TrEMBL
-
A0A3G7UFD5_9PSED
472
0
51980
TrEMBL
-
A0A3B0VY29_9ZZZZ
459
0
50877
TrEMBL
other Location (Reliability: 2)
B3QTE3_CHLT3
Chloroherpeton thalassium (strain ATCC 35110 / GB-78)
399
1
43544
TrEMBL
-
B7P885_IXOSC
153
0
17038
TrEMBL
other Location (Reliability: 3)
A0A1H1NBI3_9PSED
472
0
51839
TrEMBL
-
A0A3B0SGG9_9ZZZZ
472
0
50357
TrEMBL
other Location (Reliability: 2)
G7KP59_MEDTR
458
0
50204
TrEMBL
Chloroplast (Reliability: 3)
A0A0K2GFH2_NITMO
399
0
44437
TrEMBL
-
A0A6F8P9K9_9PSED
476
0
50188
TrEMBL
-
A0A3B0TXK8_9ZZZZ
478
0
49134
TrEMBL
other Location (Reliability: 2)
B3E6A9_TRIL1
Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)
403
0
44528
TrEMBL
-
A0A8B6GWL8_MYTGA
462
0
51440
TrEMBL
Mitochondrion (Reliability: 3)
A0A6J4P1X7_9RHOB
uncultured Rubellimicrobium sp
470
0
49518
TrEMBL
-
A0A6J4PUR6_9RHOB
uncultured Rubellimicrobium sp
119
0
12757
TrEMBL
-
W0ZDI7_9MICO
408
1
44786
TrEMBL
-
A0A386UH17_9RHOB
471
0
49924
TrEMBL
-
A0A077MC26_9MICO
392
0
41591
TrEMBL
-
E0VP15_PEDHC
461
0
51929
TrEMBL
other Location (Reliability: 3)
A0A2P6RH41_ROSCH
426
0
46795
TrEMBL
Mitochondrion (Reliability: 4)
A0A3B0UTX0_9ZZZZ
471
0
49860
TrEMBL
other Location (Reliability: 2)
E6L2T5_9PROT
392
0
44654
TrEMBL
-
K2DFD9_9BACT
147
0
17267
TrEMBL
-
G8S2J8_ACTS5
Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)
396
0
42935
TrEMBL
-
A0A812C034_SEPPH
293
0
32570
TrEMBL
other Location (Reliability: 1)
A0A3B0THP8_9ZZZZ
765
0
85045
TrEMBL
other Location (Reliability: 1)
A0A3B0USY2_9ZZZZ
443
0
47692
TrEMBL
other Location (Reliability: 4)
B0ETS0_ENTDS
Entamoeba dispar (strain ATCC PRA-260 / SAW760)
285
0
31063
TrEMBL
other Location (Reliability: 3)
A0A3G7HIP5_9PSED
472
0
51826
TrEMBL
-
A0A1G4I1W1_TRYEQ
520
0
57447
TrEMBL
other Location (Reliability: 5)
A0A3B1AZ56_9ZZZZ
478
0
52244
TrEMBL
other Location (Reliability: 1)
B9SN12_RICCO
417
0
46064
TrEMBL
Mitochondrion (Reliability: 4)
A0A6F8PCU7_PSEST
476
0
50218
TrEMBL
-
B1KDC8_SHEWM
Shewanella woodyi (strain ATCC 51908 / MS32)
378
1
40551
TrEMBL
-
A0A2G9HRC6_9LAMI
426
0
46574
TrEMBL
other Location (Reliability: 5)
A0A3B0VVL9_9ZZZZ
458
0
50795
TrEMBL
other Location (Reliability: 2)
A0A3B0RR05_9ZZZZ
477
0
50956
TrEMBL
other Location (Reliability: 3)
A0A1Y5P3C5_9MYCO
403
0
43106
TrEMBL
-
B0EN20_ENTDS
Entamoeba dispar (strain ATCC PRA-260 / SAW760)
1067
0
116473
TrEMBL
other Location (Reliability: 3)
A0A368UXC2_MARNT
Marinobacter nauticus
467
0
51668
TrEMBL
-
M2WX70_GALSU
438
0
49099
TrEMBL
Mitochondrion (Reliability: 2)
A0A1W1HC66_9DELT
433
0
48865
TrEMBL
-
A0A0T5ZI92_9CHLR
247
0
27152
TrEMBL
-
Q8RG31_FUSNN
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
338
0
38065
TrEMBL
-
A0A6F8PBH1_PSEAI
476
0
50188
TrEMBL
-
A0A3Q8IJT1_LEIDO
522
0
57329
TrEMBL
Secretory Pathway (Reliability: 5)
C7PXS8_CATAD
Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)
396
0
42323
TrEMBL
-
A0A8M1NRK2_DANRE
452
0
49517
TrEMBL
Mitochondrion (Reliability: 1)
A0A3G7A8J4_9PSED
472
0
51893
TrEMBL
-
A0A1Z5K0Q1_FISSO
282
0
31051
TrEMBL
other Location (Reliability: 3)
W8WXA6_CASDE
466
0
49347
TrEMBL
-
A0A3G2S8A7_9BASI
500
0
54816
TrEMBL
Mitochondrion (Reliability: 3)
A0A1Z5KKJ4_FISSO
308
1
34173
TrEMBL
other Location (Reliability: 5)
A0A2X3KA39_9ACTN
432
0
46154
TrEMBL
-
A9BWU6_DELAS
Delftia acidovorans (strain DSM 14801 / SPH-1)
366
1
38359
TrEMBL
-
D1C4X4_SPHTD
Sphaerobacter thermophilus (strain DSM 20745 / S 6022)
409
0
44815
TrEMBL
-
D8PHH7_9BACT
418
0
45995
TrEMBL
-
A0A1C3T4J0_BACMY
400
0
44507
TrEMBL
-
A0A0E3GYW1_9PSED
472
0
51964
TrEMBL
-
U2E205_9GAMM
396
0
42759
TrEMBL
-
A0A6N7C1Q2_9GAMM
478
0
53398
TrEMBL
-
A0A3G7YDI9_9PSED
473
0
50469
TrEMBL
-
D0MFE2_RHOM4
Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10)
399
0
44299
TrEMBL
-
A0A3B0R551_9ZZZZ
476
0
52319
TrEMBL
other Location (Reliability: 1)
A0A3G7X9V4_9PSED
464
0
50990
TrEMBL
-
Q9VJ28_DROME
455
0
50128
TrEMBL
Mitochondrion (Reliability: 2)
A0A136K0T1_9BACT
401
0
44163
TrEMBL
-
M1YWU7_NITG3
Nitrospina gracilis (strain 3/211)
424
0
47413
TrEMBL
-
A0A1W1HZD5_9BACT
418
0
46073
TrEMBL
-
A0A3B0RK00_9ZZZZ
469
0
50243
TrEMBL
other Location (Reliability: 5)
A0A386USP9_9RHOB
469
0
49411
TrEMBL
-
A0A3G7YK40_9PSED
472
0
51951
TrEMBL
-
A0A6J4HZN5_9PROT
uncultured Craurococcus sp
470
0
49565
TrEMBL
-
D3TP33_GLOMM
459
0
51535
TrEMBL
Mitochondrion (Reliability: 1)
C5C143_BEUC1
Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
390
0
41745
TrEMBL
-
A0A2S2DXZ8_9BACT
399
0
44128
TrEMBL
-
W8X0W9_CASDE
471
0
50143
TrEMBL
-
A0A8B6CIF1_MYTGA
466
0
51874
TrEMBL
Mitochondrion (Reliability: 2)
K0KEH3_WICCF
Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)
391
0
43111
TrEMBL
Mitochondrion (Reliability: 2)
C0GI06_9FIRM
375
0
41183
TrEMBL
-
A0A031IB70_9BURK
366
1
38417
TrEMBL
-
A0A3B0RYA2_9ZZZZ
345
0
36979
TrEMBL
Mitochondrion (Reliability: 3)
B2JK13_PARP8
Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)
368
1
38830
TrEMBL
-