1.1.99.24: hydroxyacid-oxoacid transhydrogenase

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For detailed information about hydroxyacid-oxoacid transhydrogenase, go to the full flat file.

Word Map on EC 1.1.99.24

1.1.99.24

gamma-hydroxybutyrate

semialdehyde

2-hydroxyglutarate

iron-containing

acidurias

oncometabolite

2-ketoglutarate

diagnostics

Reaction

Synonyms

ADHFE1, alcohol dehydrogenase iron containing 1, HOT, hydroxyacid-oxoacid transhydrogenase, iron-dependent alcohol dehydrogenase ADHFe1, transhydrogenase, hydroxy acid-oxo acid

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.99 With unknown physiological acceptors

1.1.99.24 hydroxyacid-oxoacid transhydrogenase

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Purification on EC 1.1.99.24 - hydroxyacid-oxoacid transhydrogenase

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1300fold, partial from liver

Rattus norvegicus

664967

native enzyme from liver 1300fold by precipitation using PEG 6000, anion exchange and hydrophobic interaction chromatography, and gel filtration

partial