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1.1.99.6: D-lactate dehydrogenase (acceptor)

This is an abbreviated version!
For detailed information about D-lactate dehydrogenase (acceptor), go to the full flat file.

Word Map on EC 1.1.99.6

Reaction

(R)-lactate
+
acceptor
=
pyruvate
+
reduced acceptor

Synonyms

AF0394, APE_0487, CSUB_C1080, D-2-hydroxy acid dehydrogenase, dehydrogenase, D-2-hydroxy acid, Dld enzyme, dye-DLDH, dye-linked D-lactate dehydrogenase, ST0649, TTX_0794

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.6 D-lactate dehydrogenase (acceptor)

Systematic Name

Systematic Name on EC 1.1.99.6 - D-lactate dehydrogenase (acceptor)

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SYSTEMATIC NAME
IUBMB Comments
(R)-lactate:acceptor 2-oxidoreductase
The zinc flavoprotein (FAD) from the archaeon Archaeoglobus fulgidus cannot utilize NAD+, cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. In vitro it is active with artificial electron acceptors such as 2,6-dichlorophenolindophenol, but the physiological acceptor is not yet known.