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1.10.3.11: ubiquinol oxidase (non-electrogenic)

This is an abbreviated version!
For detailed information about ubiquinol oxidase (non-electrogenic), go to the full flat file.

Word Map on EC 1.10.3.11

Reaction

2 ubiquinol +

O2
= 2 ubiquinone + 2 H2O

Synonyms

alternative oxidase, alternative oxidase 1a, alternative oxidase 1b, alternative oxidases, AOX, AOX1, AOX1a, AOX1b, AOX1C, AOX1D, AOX2, AOX2b, AOX2b1, AOX3, AppBC, AtAOX1A, CIO, CioAB, Cox2, CrAOX1, CrAOX2, cyanide-insensitive alternative oxidase, cyanide-insensitive oxidase, cyanide-insensitive quinol oxidase, cyanide-insensitive terminal quinol oxidase, cyanide-resistant alternative oxidase, cyanide-resistant bd-type ubiquinol oxidase, cyanide-resistant oxidase, cyanide-resistant ubiquinol oxidase, CydA, CydB, cytochrome ba3 oxidase, cytochrome bb3 oxidase, cytochrome bd-II, cytochrome bd-type quinol oxidase, cytochrome bo3, cytochrome bo3 ubiquinol oxidase, heme-copper terminal oxidase, mitochondrial alternative oxidase, MpAOX, plant alternative oxidase, TAO, TAOX, trypanosomal alternative oxidase, ubiquinol:oxygen oxidoreductase

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.3 With oxygen as acceptor
                1.10.3.11 ubiquinol oxidase (non-electrogenic)

IC50 Value

IC50 Value on EC 1.10.3.11 - ubiquinol oxidase (non-electrogenic)

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0000031
2,6-dihydroxy-4-[[(2E,6E,10E)-12-hydroxy-2,6,10-trimethyldodeca-2,6,10-trien-1-yl]oxy]benzoic acid
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.0011
2-fluoro-4-[[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl]oxy]benzoic acid
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.013
2-Heptyl-4-hydroxyquinoline-N-oxide
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.0024
2-hydroxy-4-[[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl]oxy]-6-methylbenzoic acid
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.0021
2-hydroxy-4-[[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl]oxy]benzoic acid
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.0000176
4-[(14-bromotetradecyl)oxy]-2-hydroxybenzaldehyde
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00092
4-[[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl]oxy]-2-methylbenzoic acid
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00000048
5-chloro-3-[(2E,6E)-8-hydroxy-3,7-dimethylnona-2,6-dienyl]-2,4-dihydroxy-6-methylbenzaldehyde
Trypanosoma brucei
pH and temperature not specified in the publication
0.017
antimycin A
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.0000037 - 0.000316
ascochlorin
-
0.000000288 - 0.000129
ascofuranone
0.00004
aurachin C 1-10
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.82
azide
Gluconobacter oxydans
-
pH 6.5, 25°C
0.0000025
colletochlorin
Trypanosoma brucei brucei
pH 7.5, 25°C
-
0.0000075 - 0.00047
colletochlorin B
-
0.00000154 - 0.00009
colletochlorin D
-
0.008 - 13
cyanide
0.00000142
ferulenol
Trypanosoma brucei brucei
pH 7.4, 25°C
-
0.04
Gramicidin S
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.013
LL-Z1272gamma
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.00169
methyl 2-hydroxy-4-[[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl]oxy]benzoate
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.0023
methyl 4-[(14-bromotetradecyl)oxy]-2-hydroxybenzoate
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00007 - 0.0001
octyl gallate
0.0000023 - 0.000862
octyl-gallate
-
0.0007
Piericidin A
Gluconobacter oxydans
at 25°C in 50 mM potassium phosphate (pH 6.5)
0.00036 - 0.00044
propyl gallate
0.00593 - 0.194
Salicylhydroxamic acid
0.0000037 - 0.047
salicylic hydroxamic acid
0.012 - 0.02
sialic acid
0.0000042
[14-(4-carboxy-3-hydroxy-5-methylphenoxy)tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00022
[14-(4-formyl-3-hydroxyphenoxy)tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00074
[14-[3-fluoro-4-(methoxycarbonyl)phenoxy]tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.000015
[14-[3-hydroxy-4-(methoxycarbonyl)phenoxy]tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.00025
[14-[4-(ethoxycarbonyl)-3-hydroxy-5-methylphenoxy]tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-
0.000012
[14-[4-hydroxy-3-(methoxycarbonyl)phenoxy]tetradecyl](triphenyl)phosphanium
Trypanosoma brucei brucei
37°C, pH not specified in the publication
-