1.10.3.4: o-aminophenol oxidase

This is an abbreviated version, for detailed information about o-aminophenol oxidase, go to the full flat file.

Reaction

4 2-aminophenol + 3 O2 = 2 2-aminophenoxazin-3-one + 6 H2O

Synonyms

2-aminophenol:oxygen oxidoreductase, esophenoxazine synthase, GriF, isophenoxazine synthase, o-aminophenol oxidase, o-aminophenol:O2 oxidoreductase, oxidase, o-aminophenol, phenoxazinone synthase, PHS, PhsA

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.3 With oxygen as acceptor
                1.10.3.4 o-aminophenol oxidase

Inhibitors

Inhibitors on EC 1.10.3.4 - o-aminophenol oxidase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,3-Dimercaptopropanol
-
-
2-Aminophenol
-
inhibitory above 0.6 mM
3-amino-4-hydroxybenzensulfonic acid
3-hydroxyanthranilic acid
4-hydroxy-3-nitrobenzaldehyde
4-hydroxybenzaldehyde
-
-
8-hydroxyquinoline
-
-
alpha,alpha'-dipyridyl
-
-
aniline
anthranilic acid
ascorbic acid
Atebrin
azide
cyanide
cysteine
DMSO
-
the native enzyme shows less than 5% residual activity in the presence of DMSO
ethanol
-
the native enzyme shows less than 5% residual activity in the presence of ethanol
ethyl acetate
-
the native enzyme shows less than 5% residual activity in the presence of ethyl acetate
glutathione
L-tyrosine
methanol
-
the native enzyme shows less than 5% residual activity in the presence of methanol
N-ethylmaleimide
o-aminophenol
-
substrate inhibition above 0.6 mM
o-Nitrophenol
-
-
p-chloromercuribenzoate
p-Hydroxybenzaldehyde
-
-
p-hydroxymercuribenzoate
phenol
Sodium diethyldithiocarbamate
-
-