1.10.3.4: o-aminophenol oxidase

This is an abbreviated version, for detailed information about o-aminophenol oxidase, go to the full flat file.

Reaction

4 2-aminophenol + 3 O2 = 2 2-aminophenoxazin-3-one + 6 H2O

Synonyms

2-aminophenol:oxygen oxidoreductase, esophenoxazine synthase, GriF, isophenoxazine synthase, o-aminophenol oxidase, o-aminophenol:O2 oxidoreductase, oxidase, o-aminophenol, phenoxazinone synthase, PHS, PhsA

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.3 With oxygen as acceptor
                1.10.3.4 o-aminophenol oxidase

Systematic Name

Systematic Name on EC 1.10.3.4 - o-aminophenol oxidase

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SYSTEMATIC NAME
IUBMB Comments
2-aminophenol:oxygen oxidoreductase
A flavoprotein which catalyses a 6-electron oxidation. The enzyme from the plant Tecoma stans requires Mn2+ and FAD [1] whereas the fungus Pycnoporus coccineus requires Mn2+ and riboflavin 5'-phosphate [2], the bacteria Streptomyces antibioticus requires Cu2+ [4] and the plant Bauhenia monandra does not require any co-factors [3].