Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.11.1.11: L-ascorbate peroxidase

This is an abbreviated version!
For detailed information about L-ascorbate peroxidase, go to the full flat file.

Word Map on EC 1.11.1.11

Reaction

2 L-ascorbate +

H2O2
+ 2 H+ = 2 monodehydroascorbate + 2 H2O

Synonyms

Am-pAPX1, APEX2, APOX, APX, APX 1, APX 2, APX1, APX2, APX3, APX4, APX5, APX6, APX7, APx8, APXS, APXT, ascorbate peroxidase, ascorbate peroxidase 1, ascorbate peroxidase 2, ascorbate peroxidase 3, ascorbate peroxidase 4, ascorbate peroxidase 5, ascorbate peroxidase 6, ascorbate peroxidase 7, ascorbate peroxidase 8, ascorbate peroxidase6, ascorbic acid peroxidase, At1g07890, AT1G77490, AT3G09640, AT4G08390, AT4G32320, AT4G35000, AT4G35970, AtAPx08, AtAPX1, AtAPX2, AtAPX3, AtAPX5, AtAPX6, AtSAPX, AtstAPX, AtTAPX, cAPX, cAPX 2, CmstAPX, CrAPX4, CreAPX1, CreAPX2, CreAPX4, CreAPXheme, CsAPX1, cytoplasmic ascorbate peroxidase 1, cytosolic ascorbate peroxidase, GhAPX1, glyoxysomal APX, HvAPX1, L-ascorbate peroxidase, L-ascorbate peroxidase 3, L-ascorbate peroxidase 5, L-ascorbate peroxidase 6, L-ascorbate peroxidase, heme-containing, L-ascorbic acid peroxidase, L-ascorbic acid-specific peroxidase, LmAPX, MaAPX1, OsAPx1, OsAPx2, OsAPx3, OsAPx4, OsAPx5, OsAPx6, OsAPx7, OsAPx8, OsAPXa, OsAPXb, pAPX, Pavirv00022559m, peroxidase, ascorbate, peroxisomal ascorbate peroxidase, PgAPX1, PHYPA_001206, PHYPA_001884, PHYPA_021776, PHYPA_024580, PHYPA_024582, Potri.002G081900, Potri.004G174500, Potri.005G112200, Potri.005G161900, Potri.005G179200, Potri.006G089000, Potri.006G132200, Potri.006G254500, Potri.009G015400, Potri.009G134100, Potri.016G084800, PpAPX, PpAPX-S, PpAPX2, PpAPX2.1, PpAPX2.2, PpAPX3, PpAPX6-related, PtAPX-S.1, PtAPX-S.2, PtAPX-TL29, PtAPX.3, PtAPX1.1, PtAPX1.2, PtAPX2, PtAPX3, PtAPX5, PtAPX5-like, PtAPX6 related, PtotAPX, RcAPX, sAPX, stromal APX, stromal ascorbate peroxidase, stromal ascorbate peroxidases, TaAPX, tAPX, thylakoid ascorbate peroxidase, thylakoid membrane-bound ascorbate peroxidases, thylakoid-bound ascorbate peroxidase

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.11 L-ascorbate peroxidase

Expression

Expression on EC 1.11.1.11 - L-ascorbate peroxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
0.01 mM diphenylene iodonium chloride treatment leads to an obvious decrease in the activity of ascorbate peroxidase in Clostera anachoreta larvae-wounded leaves
Populus simonii x Populus pyramidalis
-
abscisic acid induces ascorbate peroxidase activity
-
activity of ascorbate peroxidase is enhanced in Clostera anachoreta larvae-wounded leaves (immediate and sharp increase at 0.5 h, followed by a sudden decrease at 2 h, and then a slight increase at 6 h after damage)
Populus simonii x Populus pyramidalis
-
APX activity in the 35S-PpAPX transgenic lines increases by 50% compared to the activity in the control lines, activity is 80% higher in the leaves in response to drought or salt stresses, the PpAPX transcript level is very low under normal growing conditions in rd29Ap-PpAPX plants, but clearly increased under drought stress
APX is easily inactivated by excess amounts of H2O2, chloroplastic APX looses its activity within 1 min in the absence of ascorbate when 20 mol equivalent of H2O2 is added
-
APX6 is a bona fide senescence-associated gene. High osmotic conditions, dark stress, and abscisic acid (ABA) activate APX6 expression in an age-dependent manner. APX6 expression is specifically induced in aging leaves and in response to senescence-promoting stimuli such as abscisic acid (ABA), extended darkness, and osmotic stress. apx6 mutants showed early developmental senescence and increased sensitivity to dark stress. Mutants of squamosa promoter binding protein-like7 (SPL7), the master regulator of copper homeostasis and miR398 expression, have a higher APX6 level compared to the wild-type, which further increases under copper deficiency. miR398 is a potential post-transcriptional regulator of APX6
CrAPX4 is downregulated using amiRNA technology to examine the role of APX for high-light (HL) acclimation. The CrAPX4 knockdown amiRNA lines show low APX activity and CrAPX4 transcript level without a change in CrAPX1 and CrAPX2 transcript levels, and monodehydroascorbate reductase (MDAR), dehydroascorbate reductase (DHAR), and glutathione reductase (GR) activities and transcript levels. Upon exposure to high-light (HL), CrAPX4 knockdown amiRNA lines show a modification in the expression of genes encoding the enzymes in the ascorbate-glutathione cycle, including an increase in transcript level of CrVTC2, a key enzyme for ascorbate (AsA) biosynthesis but a decrease in MDAR and DHAR transcription and activity after 1 h, followed by increases in reactive oxygen species production and lipid peroxidation after 6 h, and exhibit cell death after 9 h. Besides, AsA content and AsA/DHA (dehydroascorbate) ratio decrease in CrAPX4 knockdown amiRNA lines after prolonged HL treatment
-
cytosolic ascorbate peroxidase 1 protein and mRNA accumulates during drought and heat stress
-
drought, Pi-free, Cd, and Xanthomonas oryzae pv. oryzicola B8-12 treatments are able to significantly alter the expression profiles of rice APX isozymes, overview
drought, Pi-free, Cd, and Xanthomonas oryzae pv. oryzicola B8-12 treatments are able to significantly alter the expression profiles of rice APX isozymes, overview. Isozyme OsAPX3 is not affected by drought stress and by Cd stress
drought, Pi-free, Cd, and Xanthomonas oryzae pv. oryzicola B8-12 treatments are able to significantly alter the expression profiles of rice APX isozymes, overview. Isozyme OsAPX5 is unaffected by drought and Cd stresses
enzyme expression is unaffected by heat stress at 50°C, but is downregulated by freezing at -20°C
-
enzyme expression markedly increases in leaves of plants subjected to conditions of long-term treatment with salinity, whereas Apx transcript levels remain unaffected in detached leaves during short-term salt treatment
-
exogenous calcium enhances rice tolerance to acid rain stress by regulating isozymes composition and transcriptional expression of ascorbate peroxidase
exogenous calcium enhances rice tolerance to acid rain stress by regulating isozymes composition and transcriptional expression of ascorbate peroxidase. Simulated acid rain (SAR)stress (pH 3.5) upregulates the expression of APX1 and APX4 in rice leaves and the expression of APX1, APX2, and APX4 in rice roots
expression increases under drought stress, with maximum levels attained 5-days after imposition of stress
expression is induced by drought, salt, and cold stresses
expression is induced by high salinity treatment
-
expression is significantly increased under NaCl stress
expression of gene decreases in response to NaCl stress
expression of LmAPX is increased when cells are treated with exogenous H2O2
expression of PgAPX1 significantly increases under heat-stress conditions, transcript analysis suggests that the heat-shock element, HSE, motifs may be responsible for stress-specific expression of PgAPX1 by interacting with PgHSF
gene DsAPX is iduced by desiccation/rehydration
-
gene expression shows the highest number of transcripts at 14°C and its decrease with elevated temperature
HvAPX1-overexpressing transgenic plants have higher APX activity in leaves under zinc stress
-
identification of potential small RNAs involved in regulating APX6 level, overview
in presence of 200 mM NaCl, expression is not significant until 24 h posttreatment
in presence of 200 mM NaCl, expression level is upregulated quickly at 12 h and gains its maximum level at 24 h posttreatment
isozyme OsAPX1 is downregulated by Cd stress
isozyme OsAPX1 is induced by drought stress
isozyme OsAPX2 is downregulated by drought and Cd stress
isozyme OsAPX4 is downregulated by drought and Cd stress
isozyme OsAPX6 is downregulated by Cd stress
isozyme OsAPX6 is slightly induced by drought stress
isozyme OsAPX7 is downregulated by Cd stress
isozyme OsAPX7 is induced by drought stress
isozyme OsAPX8 is downregulated by drought and Cd stress
no ascorbate peroxidase activity is present in mature seeds but activity is detected after 24 h post imbibition and increases 14fold up to 144 h post imbibition
RcAPX expression is significantly suppressed by galls, Galla chinensis, resulting from the galling aphid Schlechtendalia chinensis parasitizing the vein or compound leaves of Rhus chinensis
-
salt stress, Na+ induces expression of OsAPx8, , NaCl-enhanced expression of OsAPx8 in rice roots is mediated through an accumulation of the plant hormone ABA
-
salt-induced up-regulation of ascorbate peroxidase
-
simulated acid rain (SAR)stress (pH 3.5) downregulates the expression of APX2 in rice leaves and the expression of APX3 in rice roots
the application of either LaCl3 or EGTA reverses the effect of abscisic acid on chilling-treated plants, i.e. it leads to the decrease in ascorbate peroxidase activity
-
the gene expression profile of CsAPX1 encoding ascorbate peroxidase (APX) is regulated by light/dark conditions. AsA accumulation and APX activity are suppressed by light/dark conditions
there is an increase in APX (from strain IR-1) under 28°C/0.1 mM m-2 s-1 light an temperature conditions
transcript level and the total APX activity are highly induced in response to in vitro applied H2O2 or ethylene, up-regulated during fiber cell elongating