1.11.1.14: lignin peroxidase

This is an abbreviated version, for detailed information about lignin peroxidase, go to the full flat file.

Reaction

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol
+
H2O2
=
3,4-dimethoxybenzaldehyde
+
2-methoxyphenol
+
glycolaldehyde
+
H2O

Synonyms

ALiP-P3, diarylpropane oxygenase, diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving), DypB, Glg4, H2O2-dependent ligninase, lignin peroxidase, lignin peroxidase LIII, ligninase, ligninase H2, ligninase H8, ligninase I, ligninase LG5, LIP, Lip1, LIP2, lipJ, oxygenase, diarylpropane, Pr-lip1, Pr-lip4

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.14 lignin peroxidase

Inhibitors

Inhibitors on EC 1.11.1.14 - lignin peroxidase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-bipyridyl
-
complete inhibition at 10 mM
3-Amino-1,2,4-triazole
-
Ag+
-
1 mM, about 80% inhibition of native enzyme, about 15% inhibition of enzyme immobilized in xerogel matrix of trimethoxysilane and proplytetramethoxysilane
Cetyltrimethylammonium bromide
-
weak
ethylenediamine
-
complete inhibition at 10 mM
L-cysteine
-
1 mM, complete inhibition of native enzyme, about 30% inhibition of enzyme immobilized in xerogel matrix of trimethoxysilane and proplytetramethoxysilane
Manganese
-
above 0.1 mM
NaCl
-
complete inhibition at 300 mM
SDS
-
1% w/v, 72% residual activity
sodium bis (2-ethylhexyl)-sulfosuccinate
-
a mixed reversed micelle formed by anionic surfactant sodium bis (2-ethylhexyl)-sulfosuccinate and non-ionic surfactant polyoxyethylene lauryl ether (Brij30) is used to increase the catalytic activity
sodium perborate
-
5% w/v, 71% residual activity
tetramethylethylenediamine
-
complete inhibition at 8 mM
Urea
-
1% w/v, 85% residual activity
additional information
not inhibitory: chloride
-