1.11.1.20: prostamide/prostaglandin F2alpha synthase

This is an abbreviated version!
For detailed information about prostamide/prostaglandin F2alpha synthase, go to the full flat file.

Reaction

(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate

(5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dienoate

Synonyms

PGF prostamide F synthase, PM/PGFS, Pmpgfs, prostaglandin F ethanolamide synthase, prostamide F synthase, prostamide/PGF synthase, prostamide/prostaglandin F synthase

ECTree

1 Oxidoreductases

1.11 Acting on a peroxide as acceptor

1.11.1 Peroxidases

1.11.1.20 prostamide/prostaglandin F2alpha synthase

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Results	in table
2	Activating Compound
15	AA Sequence
2	Cloned(Commentary)
2	Cofactor
1	Expression
3	General Information
2	Inhibitors
5	kcat/KM [mM/s]
13	KM Value [mM]
3	Localization
1	Metals/Ions
3	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
8	Organism
8	Pathway
3	pH Optimum
1	pH Range
6	Protein Variants
3	Purification (Commentary)
1	Reaction
8	Reference
45	Source Tissue
7	Specific Activity [micromol/min/mg]
25	Substrates and Products (Substrate)
2	Subunits
15	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
11	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.11.1.20 - prostamide/prostaglandin F2alpha synthase

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(NH4)2SO4

stimulates

ammonium sulfate

the activity of the purified recombinant enzyme is stimulated about 4fold by 1.5 M ammonium sulfate

687797