1.11.1.20: prostamide/prostaglandin F2alpha synthase
This is an abbreviated version!
For detailed information about prostamide/prostaglandin F2alpha synthase, go to the full flat file.
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Synonyms
PGF prostamide F synthase, PM/PGFS, Pmpgfs, prostaglandin F ethanolamide synthase, prostamide F synthase, prostamide/PGF synthase, prostamide/prostaglandin F synthase
ECTree
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Systematic Name
Systematic Name on EC 1.11.1.20 - prostamide/prostaglandin F2alpha synthase
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thioredoxin:(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate oxidoreductase
The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2.