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1.11.1.21: catalase-peroxidase

This is an abbreviated version!
For detailed information about catalase-peroxidase, go to the full flat file.

Word Map on EC 1.11.1.21

Reaction

2 H2O2 =

O2
+ 2 H2O

Synonyms

AfKatG, BW16_04845, CAT, CAT-2, catalase -peroxidase KatG, catalase peroxidase, catalase-peroxidase, catalase/peroxidase, CP 2, CP01, CP02, CPX, CthediskatG, EC 1.11.1.7, FeSOD A, FvCP01, FvCP02, FVEG_10866, FVEG_12888, HCP, hemoprotein b-590, HPI, hydroperoxidase I, KatG, KatG1, KatG2, KatP, katX2, KpCP, PCP, Rv1908c

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.21 catalase-peroxidase

Expression

Expression on EC 1.11.1.21 - catalase-peroxidase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
addition of 0.5 mM Fe(II)-citrate to culture liquid results in 36% increase in enzyme, substrate o-dianisidine
isoniazid had almost no effect on the expression of catalase-peroxidase
the catalase-peroxidase in Neurospora crassa, CAT-2, is a developmentally regulated enzyme: both gene expression and CAT-2 activity are induced at the stationary growth phase and during adhesion of hyphae, aerial hyphae growth and conidia formation. Gene expression and CAT-2 activity are induced when the fungus is deprived of a carbon source, or when glucose is replaced by a poor carbon sources
the enzyme is induced by H2O2, best at 55°C
Thermochaetoides dissita
the KatG catalase activity of the rho mutant strain is drastically decreased
-
the katG gene is induced by hydrogen peroxide, KatG activity is constant throughout exponential growth and is induced 50fold in the stationary phase
the levels of katG transcripts are markedly increased in cells treated with a superoxide generator, menadione (0.1 mM), and to a lesser extent in those treated with organic hydroperoxides (0.1 mM tert-butyl hydroperoxide or cumene hydroperoxide) or H2O2 (0.1 mM). OxyR binds in the vicinity of the katG promoter and regulates its expression
-
the peroxidase activity of catalase-peroxidase in cells growing at the late-exponential growth phase (24 h after inoculation) decreases to 25% less than that in cells growing in the absence of isoniazid
the peroxidase activity of catalase-peroxidase in sodium nitroprusside-treated cells is 2.7fold higher than that in cells not treated with 1 mM sodium nitroprusside
transcription of the KatG gene is increased in the rho::Tn5 mutant
-
transcriptional analysis shows the induction of FvCP01, but decreased expression of FvCP02, in both mycelia and spores in the wild-type after H2O2 exposure, but this trend is reversed when the fungus is grown on germinating maize seeds. This interaction with the plant increases the expression of FvCP02, but not FvCP01, indicating that FvCP02 may be responsive to plant-derived H2O2. FvCP01 is induced more than threefold in the DFvCP02 mutant grown on germlings, suggesting that FvCP01 can compensate for the loss of FvCP02